6bq1
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Human PI4KIIIa lipid kinase complex== | |
| - | + | <StructureSection load='6bq1' size='340' side='right' caption='[[6bq1]], [[Resolution|resolution]] 3.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6bq1]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BQ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BQ1 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=E4S:5-{2-amino-1-[4-(morpholin-4-yl)phenyl]-1H-benzimidazol-6-yl}-N-(2-fluorophenyl)-2-methoxypyridine-3-sulfonamide'>E4S</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/1-phosphatidylinositol_4-kinase 1-phosphatidylinositol 4-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.67 2.7.1.67] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bq1 OCA], [http://pdbe.org/6bq1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bq1 RCSB], [http://www.ebi.ac.uk/pdbsum/6bq1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bq1 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/HYCCI_HUMAN HYCCI_HUMAN]] Hypomyelination - congenital cataract. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HYCCI_HUMAN HYCCI_HUMAN]] May have a role in the beta-catenin/Lef signaling pathway. May have a role in the process of myelination of the central and peripheral nervous system.<ref>PMID:16951682</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: 1-phosphatidylinositol 4-kinase]] | ||
| + | [[Category: Baskin, J]] | ||
| + | [[Category: Camilli, P D]] | ||
| + | [[Category: Dobbs, K]] | ||
| + | [[Category: Lees, J A]] | ||
| + | [[Category: Notarangelo, L D]] | ||
| + | [[Category: Oh, M]] | ||
| + | [[Category: Reinisch, K M]] | ||
| + | [[Category: Schauder, C M]] | ||
| + | [[Category: Walz, T]] | ||
| + | [[Category: Yu, X]] | ||
| + | [[Category: Zhang, Y]] | ||
| + | [[Category: Kinase]] | ||
| + | [[Category: Phosphoinositide synthesis]] | ||
| + | [[Category: Transferase-signaling protein complex]] | ||
Revision as of 07:04, 13 December 2017
Human PI4KIIIa lipid kinase complex
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