5fdx
From Proteopedia
(Difference between revisions)
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<StructureSection load='5fdx' size='340' side='right' caption='[[5fdx]], [[Resolution|resolution]] 2.65Å' scene=''> | <StructureSection load='5fdx' size='340' side='right' caption='[[5fdx]], [[Resolution|resolution]] 2.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5fdx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FDX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FDX FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5fdx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FDX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FDX FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5X1:3-[(4-METHYLPIPERAZIN-1-YL)METHYL]-~{N}-[(4~{R})-4-METHYL-2-PYRIMIDIN-5-YL-3,4-DIHYDRO-1~{H}-ISOQUINOLIN-7-YL]-5-(TRIFLUOROMETHYL)BENZAMIDE'>5X1</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5X1:3-[(4-METHYLPIPERAZIN-1-YL)METHYL]-~{N}-[(4~{R})-4-METHYL-2-PYRIMIDIN-5-YL-3,4-DIHYDRO-1~{H}-ISOQUINOLIN-7-YL]-5-(TRIFLUOROMETHYL)BENZAMIDE'>5X1</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fdx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fdx OCA], [http://pdbe.org/5fdx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fdx RCSB], [http://www.ebi.ac.uk/pdbsum/5fdx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fdx ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fdx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fdx OCA], [http://pdbe.org/5fdx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fdx RCSB], [http://www.ebi.ac.uk/pdbsum/5fdx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fdx ProSAT]</span></td></tr> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
| - | [[Category: | + | [[Category: Bartual, S G]] |
| - | + | ||
| - | + | ||
[[Category: Borkowska, O]] | [[Category: Borkowska, O]] | ||
| + | [[Category: Bountra, C]] | ||
| + | [[Category: Bullock, A]] | ||
[[Category: Burgess-Brown, N]] | [[Category: Burgess-Brown, N]] | ||
[[Category: Chaikuad, A]] | [[Category: Chaikuad, A]] | ||
[[Category: Chalk, R]] | [[Category: Chalk, R]] | ||
| - | [[Category: | + | [[Category: Delft, F von]] |
| - | [[Category: | + | [[Category: Ding, K]] |
[[Category: Edwards, A M]] | [[Category: Edwards, A M]] | ||
| - | [[Category: KUPINSKA, K]] | ||
[[Category: Kopec, J]] | [[Category: Kopec, J]] | ||
| + | [[Category: Kupinska, K]] | ||
[[Category: Mahajan, P]] | [[Category: Mahajan, P]] | ||
[[Category: Mukhopadhyay, S]] | [[Category: Mukhopadhyay, S]] | ||
[[Category: Newman, J]] | [[Category: Newman, J]] | ||
| - | [[Category: | + | [[Category: Pinkas, D M]] |
[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
[[Category: Sorell, F]] | [[Category: Sorell, F]] | ||
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[[Category: Tallant, C]] | [[Category: Tallant, C]] | ||
[[Category: Talon, R]] | [[Category: Talon, R]] | ||
| - | [[Category: | + | [[Category: Wang, Z]] |
[[Category: Williams, E]] | [[Category: Williams, E]] | ||
[[Category: Ddr1 kinase]] | [[Category: Ddr1 kinase]] | ||
Revision as of 07:22, 13 December 2017
Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution.
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Categories: Human | Receptor protein-tyrosine kinase | Arrowsmith, C H | Bartual, S G | Borkowska, O | Bountra, C | Bullock, A | Burgess-Brown, N | Chaikuad, A | Chalk, R | Delft, F von | Ding, K | Edwards, A M | Kopec, J | Kupinska, K | Mahajan, P | Mukhopadhyay, S | Newman, J | Pinkas, D M | Structural genomic | Sorell, F | Strain-Damerell, C | Tallant, C | Talon, R | Wang, Z | Williams, E | Ddr1 kinase | Inhibitor | Psi-biology | Sgc | Transferase
