This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5mkt
From Proteopedia
(Difference between revisions)
m (Protected "5mkt" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of mouse prorenin== | |
| - | + | <StructureSection load='5mkt' size='340' side='right' caption='[[5mkt]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5mkt]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MKT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MKT FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Renin Renin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.15 3.4.23.15] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mkt OCA], [http://pdbe.org/5mkt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mkt RCSB], [http://www.ebi.ac.uk/pdbsum/5mkt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mkt ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RENI1_MOUSE RENI1_MOUSE]] Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Renin]] | ||
[[Category: Read, R]] | [[Category: Read, R]] | ||
[[Category: Yan, Y]] | [[Category: Yan, Y]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Prorenin]] | ||
Revision as of 06:09, 20 December 2017
Crystal structure of mouse prorenin
| |||||||||||
