5oyg
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of calcium-free mTMEM16A chloride channel at 4.06 A resolution== | |
| - | + | <StructureSection load='5oyg' size='340' side='right' caption='[[5oyg]], [[Resolution|resolution]] 4.06Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5oyg]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OYG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OYG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5oyb|5oyb]]</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oyg OCA], [http://pdbe.org/5oyg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oyg RCSB], [http://www.ebi.ac.uk/pdbsum/5oyg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oyg ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ANO1_MOUSE ANO1_MOUSE]] Calcium-activated chloride channel (CaCC) which plays an important role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.<ref>PMID:18585372</ref> <ref>PMID:18724360</ref> <ref>PMID:21908539</ref> <ref>PMID:22002868</ref> <ref>PMID:22075693</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Dutzler, R]] | ||
| + | [[Category: Kalienkova, V]] | ||
| + | [[Category: Lam, K M]] | ||
| + | [[Category: Neldner, Y]] | ||
| + | [[Category: Paulino, C]] | ||
| + | [[Category: Cryo-em]] | ||
| + | [[Category: Ion channel]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: Tmem16 family]] | ||
Revision as of 06:13, 20 December 2017
Structure of calcium-free mTMEM16A chloride channel at 4.06 A resolution
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