5v3q
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Human GSTO1-1 complexed with ML175== | |
| - | + | <StructureSection load='5v3q' size='340' side='right' caption='[[5v3q]], [[Resolution|resolution]] 2.25Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5v3q]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V3Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V3Q FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLX:N-{3-[(2-chloro-acetyl)-(4-nitro-phenyl)-amino]-propyl}-2,2,2-trifluoro-acetamide'>MLX</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[ | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1eem|1eem]], [[4is0|4is0]], [[3vln|3vln]]</td></tr> |
| - | [[Category: Oakley, A | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v3q OCA], [http://pdbe.org/5v3q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v3q RCSB], [http://www.ebi.ac.uk/pdbsum/5v3q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v3q ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GSTO1_HUMAN GSTO1_HUMAN]] Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid.<ref>PMID:10783391</ref> <ref>PMID:11511179</ref> <ref>PMID:17226937</ref> <ref>PMID:18028863</ref> <ref>PMID:21106529</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Oakley, A J]] | ||
| + | [[Category: Glutathione transferase]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Ml175]] | ||
| + | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 06:16, 20 December 2017
Human GSTO1-1 complexed with ML175
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