6ap4
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the DNA polymerase III subunit beta from Acinetobacter baumannii== | |
| - | + | <StructureSection load='6ap4' size='340' side='right' caption='[[6ap4]], [[Resolution|resolution]] 2.95Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ap4]] is a 16 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AP4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AP4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | [ | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6amq|6amq]], [[6ams|6ams]]</td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ap4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ap4 OCA], [http://pdbe.org/6ap4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ap4 RCSB], [http://www.ebi.ac.uk/pdbsum/6ap4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ap4 ProSAT]</span></td></tr> |
| - | [[Category: Oakley, A | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/V5V7W3_ACIBA V5V7W3_ACIBA]] Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.[PIRNR:PIRNR000804] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: McGrath, A E]] | ||
| + | [[Category: Oakley, A J]] | ||
| + | [[Category: Dna binding]] | ||
| + | [[Category: Dna directed dna polymerase activity]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 06:23, 20 December 2017
Crystal structure of the DNA polymerase III subunit beta from Acinetobacter baumannii
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