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6bdf
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==2.8 A resolution reconstruction of the Thermoplasma acidophilum 20S proteasome using cryo-electron microscopy== | |
| - | + | <StructureSection load='6bdf' size='340' side='right' caption='[[6bdf]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6bdf]] is a 28 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BDF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BDF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Proteasome_endopeptidase_complex Proteasome endopeptidase complex], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.25.1 3.4.25.1] </span></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bdf OCA], [http://pdbe.org/6bdf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bdf RCSB], [http://www.ebi.ac.uk/pdbsum/6bdf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bdf ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PSA_THEAC PSA_THEAC]] Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The T.acidophilum proteasome is able to cleave oligopeptides after Tyr, Leu, Phe, and to a lesser extent after Glu and Arg. Thus, displays chymotrypsin-like activity and low level of caspase-like and trypsin-like activities.<ref>PMID:8999862</ref> [[http://www.uniprot.org/uniprot/PSB_THEAC PSB_THEAC]] Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The T.acidophilum proteasome is able to cleave oligopeptides after Tyr, Leu, Phe, and to a lesser extent after Glu and Arg. Thus, displays chymotrypsin-like activity and low level of caspase-like and trypsin-like activities.<ref>PMID:8999862</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Proteasome endopeptidase complex]] | ||
| + | [[Category: Campbell, M G]] | ||
| + | [[Category: Carragher, B]] | ||
[[Category: Cheng, A]] | [[Category: Cheng, A]] | ||
| - | [[Category: Potter, C | + | [[Category: Potter, C S]] |
| - | + | ||
| - | + | ||
[[Category: Veesler, D]] | [[Category: Veesler, D]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Proteasome]] | ||
Revision as of 08:38, 27 December 2017
2.8 A resolution reconstruction of the Thermoplasma acidophilum 20S proteasome using cryo-electron microscopy
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