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Aldehyde dehydrogenase
From Proteopedia
(Difference between revisions)
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| - | <StructureSection load=' | + | <StructureSection load='' size='450' side='right' scene='44/447036/Cv/2' caption='Aldehyde hydrogenase class 1 tetramer complex with NAD, dithiothreitol and dimercaptobutane-diol, [[1o9j]]'> |
== Function == | == Function == | ||
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**[[4cbb]] - Betaine-PaALDH - ''Pseudomonas aeruginosa''<br /> | **[[4cbb]] - Betaine-PaALDH - ''Pseudomonas aeruginosa''<br /> | ||
**[[1a4s]] - Betaine-cALDH - cod<BR /> | **[[1a4s]] - Betaine-cALDH - cod<BR /> | ||
| - | **[[ | + | **[[3vos]], [[3tz6]], [[3vos]] – Aspartate-semi-MtALDH<BR /> |
**[[2cq8]] - Formyltetrahydrofolate-hALDH PP-binding domain - NMR<BR /> | **[[2cq8]] - Formyltetrahydrofolate-hALDH PP-binding domain - NMR<BR /> | ||
**[[2nac]] – Formate-PsALDH<BR /> | **[[2nac]] – Formate-PsALDH<BR /> | ||
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**[[3u4j]], [[4i3t]] – SmALDH – ''Sinorhizobium meliloti''<br /> | **[[3u4j]], [[4i3t]] – SmALDH – ''Sinorhizobium meliloti''<br /> | ||
**[[5dru]] - CpALDH – ''Clostridium phytofermentans''<br /> | **[[5dru]] - CpALDH – ''Clostridium phytofermentans''<br /> | ||
| - | **[[4qf6]], [[ | + | **[[4qf6]], [[5gt6]] – BcALDH – ''Bacillus cereus''<br /> |
**[[4qet]] – BcALDH (mutant)<br /> | **[[4qet]] – BcALDH (mutant)<br /> | ||
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**[[5dbv]] - CpALDH + CoA <br /> | **[[5dbv]] - CpALDH + CoA <br /> | ||
**[[4i3u]] – SmALDH + phosphonoacetaldehyde<br /> | **[[4i3u]] – SmALDH + phosphonoacetaldehyde<br /> | ||
| - | **[[ | + | **[[5gtk]] – BcALDH + NAD<br /> |
*NAD-dependent ALDH ternary complexes | *NAD-dependent ALDH ternary complexes | ||
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**[[2o2p]] – Formyltetrahydrofolate-rALDH C-terminal<br /> | **[[2o2p]] – Formyltetrahydrofolate-rALDH C-terminal<br /> | ||
**[[2y51]], [[2y52]], [[2y53]], [[2y5d]] – BxALDH (mutant) – ''Burkholderia xenovorans''<br /> | **[[2y51]], [[2y52]], [[2y53]], [[2y5d]] – BxALDH (mutant) – ''Burkholderia xenovorans''<br /> | ||
| - | **[[ | + | **[[4v6h]] - Succinate–semi-ALDH – ''Burkholderia pseudomallei''<br /> |
**[[3rh9]] - Succinate–semi-ALDH – ''Marinobacter aquaeolei''<br /> | **[[3rh9]] - Succinate–semi-ALDH – ''Marinobacter aquaeolei''<br /> | ||
**[[3uw3]] - aspartate–semi-BtALDH – ''Burkholderia thailandensis''<br /> | **[[3uw3]] - aspartate–semi-BtALDH – ''Burkholderia thailandensis''<br /> | ||
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**[[2wox]], [[2wme]], [[2xdr]], [[3zqa]] - Betaine-PaALDH + NADP<BR /> | **[[2wox]], [[2wme]], [[2xdr]], [[3zqa]] - Betaine-PaALDH + NADP<BR /> | ||
| - | **[[3lv1]] – Benzaldehyde-PpALDH3 + NADP – ''Pseudomonas putida''<BR /> | ||
**[[2ilu]] - Lactaldehyde-EcALDH + NADP<BR /> | **[[2ilu]] - Lactaldehyde-EcALDH + NADP<BR /> | ||
**[[3rhd]] - Lactaldehyde-MjALDH + NADP - ''Methanocaldococcus jannaschii''<br /> | **[[3rhd]] - Lactaldehyde-MjALDH + NADP - ''Methanocaldococcus jannaschii''<br /> | ||
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**[[5jry]] - ALDH + NADP – ''Burkholderia multivorans''<br /> | **[[5jry]] - ALDH + NADP – ''Burkholderia multivorans''<br /> | ||
**[[5j6b]] - BtALDH + NADP <br /> | **[[5j6b]] - BtALDH + NADP <br /> | ||
| - | **[[ | + | **[[5gtl]] – BcALDH + NADP<br /> |
*NADP-dependent ALDH ternary complexes | *NADP-dependent ALDH ternary complexes | ||
| - | + | ||
**[[2imp]] - Lactaldehyde-EcALDH + NADH + lactate<BR /> | **[[2imp]] - Lactaldehyde-EcALDH + NADH + lactate<BR /> | ||
**[[2vro]] – BxALDH + NADP + alcohol <br /> | **[[2vro]] – BxALDH + NADP + alcohol <br /> | ||
Revision as of 17:33, 28 December 2017
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3D Structures of Aldehyde dehydrogenase
Updated on 28-December-2017
References
- ↑ Keller, Markus A.; Zander, Ulrich; Fuchs, Julian E.; Kreutz, Christoph; Watschinger, Katrin et al. (2014). A gatekeeper helix determines the substrate specificity of Sjögren–Larsson Syndrome enzyme fatty aldehyde dehydrogenase. Nature Communications vol. 5.
