Beta-lactamase

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<StructureSection load='3spu' size='350' side='right' scene='45/453531/Cv/1' caption='Class B β-lactamase Ndm-1 complex with Zn+2 (grey) (PDB code [[3spu]])'>
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<StructureSection load='' size='350' side='right' scene='45/453531/Cv/1' caption='Class B β-lactamase Ndm-1 complex with Zn+2 (grey) (PDB code [[3spu]])'>
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__TOC__
== Function ==
== Function ==
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**[[3iof]], [[1x8i]], [[3iog]]– AhBlac B (mutant) + inhibitor<br />
**[[3iof]], [[1x8i]], [[3iog]]– AhBlac B (mutant) + inhibitor<br />
**[[1x8g]], [[2gkl]], [[2qds]] – AhBlac B + inhibitor<br />
**[[1x8g]], [[2gkl]], [[2qds]] – AhBlac B + inhibitor<br />
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**[[3m8t]] – BjBlac B + inhibitor<br />
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**[[5wcm]] – BjBlac B + inhibitor<br />
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**[[2m5d]], [[4c1c]], [[4c1h]], [[4nq5]], [[4nq6]], [[4nq7]], [[4tyt]] - BcBlac B + inhibitor<br />
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**[[2m5d]], [[4c1c]], [[4c1h]], [[4nq5]], [[4nq6]], [[5w8w]], [[4tyt]] - BcBlac B + inhibitor<br />
**[[3q6v]] – SfBlac B + glycerol <br />
**[[3q6v]] – SfBlac B + glycerol <br />
**[[3q6x]], [[4ey2]], [[4eyb]], [[4eyf]], [[4efl]], [[4hl1]], [[4hl2]] – KpBlac B Ndm-1+ antibiotic<br />
**[[3q6x]], [[4ey2]], [[4eyb]], [[4eyf]], [[4efl]], [[4hl1]], [[4hl2]] – KpBlac B Ndm-1+ antibiotic<br />

Revision as of 18:15, 28 December 2017

Class B β-lactamase Ndm-1 complex with Zn+2 (grey) (PDB code 3spu)

Drag the structure with the mouse to rotate

3D Structures of Beta-lactamase

Updated on 28-December-2017

4mll - KpBlac D Oxa-1 + antibiotic

References

  1. King D, Strynadka N. Crystal structure of New Delhi metallo-beta-lactamase reveals molecular basis for antibiotic resistance. Protein Sci. 2011 Sep;20(9):1484-91. doi: 10.1002/pro.697. Epub 2011 Aug, 2. PMID:21774017 doi:10.1002/pro.697

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Jaime Prilusky, Alexander Berchansky, Joel L. Sussman

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