SelB
From Proteopedia
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[[1lva]] – MtSelB C terminal – ''Moorella thermoacetica''<br /> | [[1lva]] – MtSelB C terminal – ''Moorella thermoacetica''<br /> | ||
[[2v9v]] - MtSelB winged-helix domains<br /> | [[2v9v]] - MtSelB winged-helix domains<br /> | ||
| - | [[ | + | [[4aca]] – MmSelB – ''Methanococcus maripaludis'' |
===SelB complex with nucleotides=== | ===SelB complex with nucleotides=== | ||
| - | [[ | + | [[4ac9]] – MmSelB + GDP <br /> |
| - | [[ | + | [[4acb]] – MmSelB + GPPNHP<br /> |
[[1wsu]], [[2uwm]] - MtSelB C terminal + RNA<br /> | [[1wsu]], [[2uwm]] - MtSelB C terminal + RNA<br /> | ||
[[2pjp]] – EcSelB mRNA-binding domain + RNA – ''Eschrichia coli''<br /> | [[2pjp]] – EcSelB mRNA-binding domain + RNA – ''Eschrichia coli''<br /> | ||
Revision as of 19:05, 28 December 2017
Elongation factor SelB uses several methods to recognize the selenocysteine insertion sequence found in messenger RNA. The insertion sequence forms a hairpin loop with an unstacked guanine base in the loop. This guanine forms The planar base is also sandwiched between in the protein, which form a tight hydrophobic pocket. This is best seen using a The overall shape of the hairpin is recognized by contacts with several In particular, notice the intimate contact formed by both the charged nitrogen and hydrophobic carbon chain of
This page complements the article on Selenocysteine Synthase in the Molecule of the Month Series. See also Teaching Scenes, Tutorials, and Educators' Pages.
3D structures of SelB
1lva – MtSelB C terminal – Moorella thermoacetica
2v9v - MtSelB winged-helix domains
4aca – MmSelB – Methanococcus maripaludis
SelB complex with nucleotides
4ac9 – MmSelB + GDP
4acb – MmSelB + GPPNHP
1wsu, 2uwm - MtSelB C terminal + RNA
2pjp – EcSelB mRNA-binding domain + RNA – Eschrichia coli
2ply - EcSelB mRNA-binding domain (mutant) + RNA
Additional Resources
For additional information, see: Translation
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Eran Hodis, David S. Goodsell, Joel L. Sussman, David Canner, Eric Martz, Alexander Berchansky
