Ribosome inactivating protein

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Line 49: Line 49:
**[[5ilx]], [[4o0o]] – bgRIP + uracil derivative<br />
**[[5ilx]], [[4o0o]] – bgRIP + uracil derivative<br />
**[[5cso]], [[5cst]] – bgRIP + cytidine<br />
**[[5cso]], [[5cst]] – bgRIP + cytidine<br />
-
**[[4kjh]] – bgRIP + cytosine<br />
+
**[[4zt8]] – bgRIP + cytosine<br />
-
**[[4zt8]] – bgα-RIP + pyrimidine derivative + cytosine <br />
+
**[[4zu0]], [[4zz6]], [[4z44]], [[4o4q]], [[4o8e]], [[4q9f]], [[1mrg]], [[3q4p]], [[3qji]], [[4emf]], [[4emr]], [[5cso]], [[5cst]], [[5ilw]], [[5ilx]] – bgα-RIP + nucleotide <br />
**[[4zu0]], [[4zz6]], [[4z44]], [[4o4q]], [[4o8e]], [[4q9f]], [[1mrg]], [[3q4p]], [[3qji]], [[4emf]], [[4emr]], [[5cso]], [[5cst]], [[5ilw]], [[5ilx]] – bgα-RIP + nucleotide <br />
Line 78: Line 77:
**[[1mrh]] – bpα-RIP + formycin<br />
**[[1mrh]] – bpα-RIP + formycin<br />
**[[4fz9]], [[4xy7]] – bgα-RIP + disaccharide <br />
**[[4fz9]], [[4xy7]] – bgα-RIP + disaccharide <br />
-
**[[4zt8]] – bgα-RIP + pyrimidine derivative + cytosine <br />
 
**[[5cf9]] – bgα-RIP + NADP <br />
**[[5cf9]] – bgα-RIP + NADP <br />

Revision as of 20:36, 28 December 2017

Ribosome inactivating protein from pokeweed complex with adenine (PDB code 1qci)

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3D Structures of ribosome inactivating protein

Updated on 28-December-2017

References

  1. Stirpe F, Barbieri L. Ribosome-inactivating proteins up to date. FEBS Lett. 1986 Jan 20;195(1-2):1-8. PMID:3510899
  2. Wang S, Zheng Y, Yan J, Zhu Z, Wu Z, Ding Y. Alpha-momorcharin: a ribosome-inactivating protein from Momordica charantia, possessing DNA cleavage properties. Protein Pept Lett. 2013 Nov;20(11):1257-63. PMID:23777339
  3. Ng TB, Liu WK, Sze SF, Yeung HW. Action of alpha-momorcharin, a ribosome inactivating protein, on cultured tumor cell lines. Gen Pharmacol. 1994 Jan;25(1):75-7. PMID:8026716
  4. Kurinov IV, Myers DE, Irvin JD, Uckun FM. X-ray crystallographic analysis of the structural basis for the interactions of pokeweed antiviral protein with its active site inhibitor and ribosomal RNA substrate analogs. Protein Sci. 1999 Sep;8(9):1765-72. PMID:10493577

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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