Calcium uptake protein
From Proteopedia
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== Function == | == Function == | ||
| - | '''Calcium uptake protein''' (CBARA1) is essential in preventing mitochondrial Ca+2 overload<ref>PMID:24336167</ref>. For more details see [[ | + | '''Calcium uptake protein''' (CBARA1) is essential in preventing mitochondrial Ca+2 overload<ref>PMID:24336167</ref>. For more details see [[Calcium uptake protein]]. |
== Disease == | == Disease == | ||
Revision as of 10:15, 1 January 2018
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3D Structures of calcium uptake protein 1
Updated on 01-January-2018
4nsc – hCBARA1 - human
4nsd – hCBARA1 + Ca
References
- ↑ Logan CV, Szabadkai G, Sharpe JA, Parry DA, Torelli S, Childs AM, Kriek M, Phadke R, Johnson CA, Roberts NY, Bonthron DT, Pysden KA, Whyte T, Munteanu I, Foley AR, Wheway G, Szymanska K, Natarajan S, Abdelhamed ZA, Morgan JE, Roper H, Santen GW, Niks EH, van der Pol WL, Lindhout D, Raffaello A, De Stefani D, den Dunnen JT, Sun Y, Ginjaar I, Sewry CA, Hurles M, Rizzuto R, Duchen MR, Muntoni F, Sheridan E. Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling. Nat Genet. 2014 Feb;46(2):188-93. doi: 10.1038/ng.2851. Epub 2013 Dec 15. PMID:24336167 doi:http://dx.doi.org/10.1038/ng.2851
- ↑ Wang L, Yang X, Li S, Wang Z, Liu Y, Feng J, Zhu Y, Shen Y. Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake. EMBO J. 2014 Feb 10. PMID:24514027 doi:http://dx.doi.org/10.1002/embj.201386523
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