5w7a
From Proteopedia
(Difference between revisions)
m (Protected "5w7a" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Rabbit acyloxyacyl hydrolase (AOAH), proteolytically processed, S262A mutant, with LPS (low quality saposin domain)== | |
| - | + | <StructureSection load='5w7a' size='340' side='right' caption='[[5w7a]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5w7a]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W7A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5W7A FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FTT:3-HYDROXY-TETRADECANOIC+ACID'>FTT</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acyloxyacyl_hydrolase Acyloxyacyl hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.77 3.1.1.77] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5w7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w7a OCA], [http://pdbe.org/5w7a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5w7a RCSB], [http://www.ebi.ac.uk/pdbsum/5w7a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5w7a ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/AOAH_RABIT AOAH_RABIT]] Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides (LPS). By breaking down LPS, terminates the host response to bacterial infection and prevents prolonged and damaging inflammatory responses. In peritoneal macrophages, seems to be important for recovery from a state of immune tolerance following infection by Gram-negative bacteria.[UniProtKB:O35298] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Acyloxyacyl hydrolase]] | ||
| + | [[Category: Gorelik, A]] | ||
| + | [[Category: Illes, K]] | ||
| + | [[Category: Nagar, B]] | ||
| + | [[Category: Gdsl esterase]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Lipopolysaccharide]] | ||
| + | [[Category: Lp]] | ||
| + | [[Category: Saposin]] | ||
Revision as of 05:47, 3 January 2018
Rabbit acyloxyacyl hydrolase (AOAH), proteolytically processed, S262A mutant, with LPS (low quality saposin domain)
| |||||||||||
