Hormone

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===Follicle-Stimulating Hormone===
===Follicle-Stimulating Hormone===
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[[1fl7]] - Follicle-Stimulating Hormone – human<br />
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[[Follicle-stimulating hormone]]
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[[1xwd]] - Human Follicle Stimulating Hormone complexed with the Leucine-repeat region of the binding domain of its receptor– human<br />
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{{Structure
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|PDB=
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|SIZE=380|SCENE=Human_Follicle-Stimulating_Hormone_Complexed_with_its_Receptor/1fl7to1xwdmorph/4|CAPTION= FSH binding to the leucine-rich domain of Follicle Stimulating Hormone Receptor ([[1fl7]] morphing to [[1xwd]], [[resolution]] 2.92&Aring;)
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE=
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|DOMAIN=
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|RELATEDENTRY=
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|RESOURCES=
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|COORDINATES=
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}}
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[[Human Follicle-Stimulating Hormone Complexed with its Receptor]] is featured [[Human Follicle-Stimulating Hormone Complexed with its Receptor|here]].<br />
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[[4ay9]] - Human Follicle Stimulating Hormone complexed with the entire ectodomain of its receptor – human<br />
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===PACAP/glucagon family of peptide hormones===
===PACAP/glucagon family of peptide hormones===
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===Glucocorticoid===
===Glucocorticoid===
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[[3mne]], [[3mno]], [[3mnp]] - Glucocorticoid Receptor Ligand-binding Domain – human<br />
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[[Glucocorticoid receptor]]
===Glucose-dependent Insulinotropic Polypeptide===
===Glucose-dependent Insulinotropic Polypeptide===
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===Growth Hormone===
===Growth Hormone===
[[Human growth hormone]] is featured [[Human growth hormone|here]].<br />
[[Human growth hormone]] is featured [[Human growth hormone|here]].<br />
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[[3hhr]] - Growth Hormone complexed with the extracellular portion of its receptor - human<br />
 
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[[1hwh]],[[1a22]] - Growth Hormone Mutant G120R complexed with the extracellular portion of its receptor - human<br />
 
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[[1bp3]] - Growth Hormone complexed with the prolactin receptor - human<br />
 
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[[3mjg]], [[3mjk]] - Platelet-derived Growth Factor/Propeptide Complex and a Platelet-Derived Growth Factor/Receptor Complex – human<br />
 
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Vascular Endothelial Growth Factor – human and others, see [[VEGF#3D_Structures_of_VEGF|Vascular Endothelial Growth Factor Structures]]<br />
 
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Vascular Endothelial Growth Factor Receptor – human, see [[VEGFR#Additional_3D_Structures_of_VEGFR|Vascular Endothelial Growth Factor Receptor Structures]]<br />
 
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[[2xdg]] - Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor – human<br />
 
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[[1axi]] – HGH (mutant) + HGH receptor (mutant)<br />
 
===Insulin===
===Insulin===
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[[3ir0]] , [[1mso]] , [[1trz]] , [[2qiu]] , [[2r34]], [[2r35]] , [[2r36]], [[3ilg]], [[2kjj]] , [[2kju]] - Insulin – human<br />
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[[Insulin]]
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[[3nw5]], [[3nw6]], [[3nw7]] - insulin-like growth factor 1 receptor – human<br />
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[[4zxb]] - insulin receptor ectodomain – human<br />
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[[Glucose-dependent Insulinotropic Polypeptide Receptor]]
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===Progesterone===
===Progesterone===

Revision as of 11:36, 14 January 2018

In the field of modern endocrinology, a hormone is any substance, generated either externally or internally, that operates via a receptor at the cellular level, which conveys to to the cell a message to stop, start, or modulate a cellular process.

Contents

Guide to Proteopedia Pages Concerning Hormones and their Receptors

Articles in Proteopedia concerning Hormone include:


To view automatically seeded indices concerning Hormone, see:


Additional 3D Structures of Hormones and Hormone Receptors and Related Molecules

Adrenaline

Beta-2 Adrenergic Receptor
The human β2 adrenergic receptor bound to a hormone analog and G-protein (3sn6) is featured in an image on the right, and additional structures are on the Adrenergic receptor page.

 

Drag the structure with the mouse to rotate
An activated G protein-coupled receptor (human β-2 adrenergic receptor in blue ) in a complex with a heterotrimeric G protein (3 subunits:reddish to orange-brown) and hormone (gold) (3sn6), resolution 3.2Å. The boundaries of the membrane in which the GPCR sits are represented in light green.



Angiotensinogen

2wxw, 2wxx, 2wxy, 2wxz, 2wy0, 2wy1, 2x0b - Angiotensinogen – human, rat, mouse

Chorionic Gonadotropin

1hrp - Chorionic Gonadotropin – human
1hcn - Chorionic Gonadotropin – human
1hd4 - Alpha-subunit of Chorionic Gonadotropin – human

Estrogen-related Receptor

Estrogen-related receptor – human and others, see Estrogen-related receptor structures

Androgen Receptor

Nuclear Androgen Receptor

Farnesoid X Receptor

3olf, 3omk, 3omm, 3oof, 3ook, 3okh, 3oki - Farnesoid X Receptor – human

Follicle-Stimulating Hormone

Follicle-stimulating hormone

PACAP/glucagon family of peptide hormones

3n94 - PAC1R, receptor of pituitary adenylate cyclase activating polypeptide, is a case of a crystal structure disagreeing with the NMR structure 2jod and vice versa
2jod - Pituitary adenylate cyclase-activating polypeptide (residues 6'-38') complexed to the extracellular

Glucocorticoid

Glucocorticoid receptor

Glucose-dependent Insulinotropic Polypeptide

Glucose-dependent Insulinotropic Polypeptide Receptor

Growth Hormone

Human growth hormone is featured here.

Insulin

Insulin

Progesterone

3hq5, 3g8o, 3hq5 - Progesterone – human

Thyroid-Stimulating hormone

3g04 - TSH receptor in complex with a thyroid-stimulating autoantibody – human
2xwt - TSH receptor in complex with a thyroid-inactivating autoantibody – human

Thyroid hormone

2nll - DNA-Binding domain in complex with an inverted repeat class of thyroid response element– rat
1xzx

Thyroxine

2xn3, 2xn5, 2xn6, 2xn7 - Thyroxine-binding Globulin – human


domain of the human splice variant hPAC1-RS determined by NMR - human



ADD 3dzu

See Also


External Resources

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