5ui1
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Human Protein Phosphatase 5C (PP5C) in complex with a triazole inhibitor== | |
| - | + | <StructureSection load='5ui1' size='340' side='right' caption='[[5ui1]], [[Resolution|resolution]] 1.96Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ui1]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UI1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UI1 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8D4:5-phenyl-1H-1,2,3-triazole-4-carboxylic+acid'>8D4</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoprotein_phosphatase Phosphoprotein phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.16 3.1.3.16] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ui1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ui1 OCA], [http://pdbe.org/5ui1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ui1 RCSB], [http://www.ebi.ac.uk/pdbsum/5ui1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ui1 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PPP5_HUMAN PPP5_HUMAN]] May play a role in the regulation of RNA biogenesis and/or mitosis. In vitro, dephosphorylates serine residues of skeletal muscle phosphorylase and histone H1. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Phosphoprotein phosphatase]] | ||
| + | [[Category: Banerjee, S]] | ||
| + | [[Category: Chattopadhyay, D]] | ||
| + | [[Category: Honkanen, R E]] | ||
| + | [[Category: Salter, E A]] | ||
| + | [[Category: Swingle, M R]] | ||
| + | [[Category: Hysrolase-hydrolase inhibitor complex]] | ||
| + | [[Category: Inhibitor complex]] | ||
| + | [[Category: Pp5c]] | ||
| + | [[Category: Protein phosphatase]] | ||
Revision as of 06:52, 17 January 2018
Crystal Structure of Human Protein Phosphatase 5C (PP5C) in complex with a triazole inhibitor
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