6bcz

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<StructureSection load='6bcz' size='340' side='right' caption='[[6bcz]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
<StructureSection load='6bcz' size='340' side='right' caption='[[6bcz]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6bcz]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BCZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BCZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6bcz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BCZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BCZ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D7Y:tert-butyl+(2-{[(2R)-3-oxo-2-[(propan-2-yl)amino]-3-{[(pyridin-3-yl)methyl]amino}propyl]sulfanyl}ethyl)carbamate'>D7Y</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D7Y:tert-butyl+(2-{[(2R)-3-oxo-2-[(propan-2-yl)amino]-3-{[(pyridin-3-yl)methyl]amino}propyl]sulfanyl}ethyl)carbamate'>D7Y</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6bd6|6bd6]], [[6bd5|6bd5]], [[6bd7|6bd7]], [[6bd8|6bd8]], [[6bdh|6bdh]], [[6bdi|6bdi]], [[6bdk|6bdk]], [[6bdm|6bdm]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6bd6|6bd6]], [[6bd5|6bd5]], [[6bd7|6bd7]], [[6bd8|6bd8]], [[6bdh|6bdh]], [[6bdi|6bdi]], [[6bdk|6bdk]], [[6bdm|6bdm]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CYP3A4, CYP3A3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bcz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bcz OCA], [http://pdbe.org/6bcz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bcz RCSB], [http://www.ebi.ac.uk/pdbsum/6bcz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bcz ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bcz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bcz OCA], [http://pdbe.org/6bcz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bcz RCSB], [http://www.ebi.ac.uk/pdbsum/6bcz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bcz ProSAT]</span></td></tr>
</table>
</table>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
[[Category: Sevrioukova, I]]
[[Category: Sevrioukova, I]]
[[Category: Inhibitor]]
[[Category: Inhibitor]]
[[Category: Monooxygenase]]
[[Category: Monooxygenase]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]

Revision as of 08:24, 17 January 2018

Crystal structure of human CYP3A4 bound to an inhibitor

6bcz, resolution 2.23Å

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