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1j1h

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Revision as of 08:51, 17 January 2018

Solution structure of a tmRNA-binding protein, SmpB, from Thermus thermophilus

Structural highlights

1j1h is a 1 chain structure with sequence from "flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

[SSRP_THET8] Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

Small protein B (SmpB) is required for trans-translation, binding specifically to tmRNA. We show here the solution structure of SmpB from an extremely thermophilic bacterium, Thermus thermophilus HB8, determined by heteronuclear nuclear magnetic resonance methods. The core of the protein consists of an antiparallel beta-barrel twisted up from eight beta-strands, each end of which is capped with the second or third helix, and the first helix is located beside the barrel. Its C-terminal sequence (20 residues), which is rich in basic residues, shows a poorly structured form, as often seen in isolated ribosomal proteins. The results are discussed in relation to the oligonucleotide binding fold.

Solution structure of a tmRNA-binding protein, SmpB, from Thermus thermophilus.,Someya T, Nameki N, Hosoi H, Suzuki S, Hatanaka H, Fujii M, Terada T, Shirouzu M, Inoue Y, Shibata T, Kuramitsu S, Yokoyama S, Kawai G FEBS Lett. 2003 Jan 30;535(1-3):94-100. PMID:12560085^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Someya T, Nameki N, Hosoi H, Suzuki S, Hatanaka H, Fujii M, Terada T, Shirouzu M, Inoue Y, Shibata T, Kuramitsu S, Yokoyama S, Kawai G. Solution structure of a tmRNA-binding protein, SmpB, from Thermus thermophilus. FEBS Lett. 2003 Jan 30;535(1-3):94-100. PMID:12560085

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1j1h"

@@ Line 1: / Line 1: @@
 ==Solution structure of a tmRNA-binding protein, SmpB, from Thermus thermophilus==
 <StructureSection load='1j1h' size='340' side='right' caption='[[1j1h]], [[NMR_Ensembles_of_Models | 11 NMR models]]' scene=''>
 == Structural highlights ==
 <table><tr><td colspan='2'>[[1j1h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J1H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J1H FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j1h OCA], [http://pdbe.org/1j1h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1j1h RCSB], [http://www.ebi.ac.uk/pdbsum/1j1h PDBsum], [http://www.topsan.org/Proteins/RSGI/1j1h TOPSAN]</span></td></tr>
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j1h OCA], [http://pdbe.org/1j1h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1j1h RCSB], [http://www.ebi.ac.uk/pdbsum/1j1h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1j1h ProSAT], [http://www.topsan.org/Proteins/RSGI/1j1h TOPSAN]</span></td></tr>
 </table>
 == Function ==
@@ Line 11: / Line 12: @@
 Check<jmol>
   <jmolCheckbox>
-    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j1/1j1h_consurf.spt"</scriptWhenChecked>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j1/1j1h_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>

1j1h

From Proteopedia

Revision as of 08:51, 17 January 2018

Solution structure of a tmRNA-binding protein, SmpB, from Thermus thermophilus

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

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