A-kinase anchor protein

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 13: Line 13:
== Structural highlights ==
== Structural highlights ==
-
An ampiphatic helix of AKAP18 binds with its hydrophobic sides to helices of the PKA regulatory subunit<ref>PMID:27102985</ref>.
+
An <scene name='77/777613/Cv/5'>ampiphatic helix of AKAP18 binds with its hydrophobic sides to helices of the PKA regulatory subunit</scene><ref>PMID:27102985</ref>.
</StructureSection>
</StructureSection>

Revision as of 14:47, 24 January 2018

Human AKAP18 helix (deepskyblue) complex with a dimer of cAMP-dependent protein kinase regulatory subunit (magenta and green) and Cd+2 ions (PDB code 4zp3)

Drag the structure with the mouse to rotate

3D Structures of A-kinase anchor protein

Updated on 24-January-2018

References

  1. ↑ Edwards AS, Scott JD. A-kinase anchoring proteins: protein kinase A and beyond. Curr Opin Cell Biol. 2000 Apr;12(2):217-21. PMID:10712918
  2. ↑ Carr DW, Newell AE. The role of A-kinase anchoring proteins (AKaps) in regulating sperm function. Soc Reprod Fertil Suppl. 2007;63:135-41. PMID:17566268
  3. ↑ Diviani D, Dodge-Kafka KL, Li J, Kapiloff MS. A-kinase anchoring proteins: scaffolding proteins in the heart. Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H1742-53. doi:, 10.1152/ajpheart.00569.2011. Epub 2011 Aug 19. PMID:21856912 doi:http://dx.doi.org/10.1152/ajpheart.00569.2011
  4. ↑ Gotz F, Roske Y, Schulz MS, Autenrieth K, Bertinetti D, Faelber K, Zuhlke K, Kreuchwig A, Kennedy E, Krause G, Daumke O, Herberg FW, Heinemann U, Klussmann E. AKAP18:PKA-RIIalpha structure reveals crucial anchor points for recognition of regulatory subunits of PKA. Biochem J. 2016 Apr 21. pii: BCJ20160242. PMID:27102985 doi:http://dx.doi.org/10.1042/BCJ20160242

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/A-kinase_anchor_protein"
Personal tools