6bev
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Human Single Domain Sulfurtranferase TSTD1== | |
| - | + | <StructureSection load='6bev' size='340' side='right' caption='[[6bev]], [[Resolution|resolution]] 1.04Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6bev]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BEV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BEV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bev OCA], [http://pdbe.org/6bev PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bev RCSB], [http://www.ebi.ac.uk/pdbsum/6bev PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bev ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TSTD1_HUMAN TSTD1_HUMAN]] Thiosulfate:glutathione sulfurtransferase (TST) required to produce glutathione persulfide (GSS(-)), a central intermediate in hydrogen sulfide metabolism (PubMed:24981631). Provides the link between the first step in mammalian H(2)S metabolism performed by the sulfide:quinone oxidoreductase (SQOR) which catalyzes the conversion of H(2)S to thiosulfate, and the sulfur dioxygenase (SDO) which uses GSS(-) as substrate (PubMed:24981631). The thermodynamic coupling of the irreversible SDO and reversible TST reactions provides a model for the physiologically relevant reaction with thiosulfate as the sulfane donor (PubMed:24981631).<ref>PMID:24981631</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Akey, D L]] | ||
| + | [[Category: Banerjee, R]] | ||
| + | [[Category: Motl, N]] | ||
| + | [[Category: Smith, J L]] | ||
| + | [[Category: Sulfurtransferase]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 18:29, 24 January 2018
Human Single Domain Sulfurtranferase TSTD1
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