2c6b

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==SOLUTION STRUCTURE OF THE C4 ZINC-FINGER DOMAIN OF HDM2==
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==Solution structure of the C4 zinc-finger domain of HDM2==
<StructureSection load='2c6b' size='340' side='right' caption='[[2c6b]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2c6b' size='340' side='right' caption='[[2c6b]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rv1|1rv1]], [[1t4e|1t4e]], [[1t4f|1t4f]], [[1ycr|1ycr]], [[1z1m|1z1m]], [[2c6a|2c6a]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rv1|1rv1]], [[1t4e|1t4e]], [[1t4f|1t4f]], [[1ycr|1ycr]], [[1z1m|1z1m]], [[2c6a|2c6a]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c6b OCA], [http://pdbe.org/2c6b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c6b RCSB], [http://www.ebi.ac.uk/pdbsum/2c6b PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c6b OCA], [http://pdbe.org/2c6b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c6b RCSB], [http://www.ebi.ac.uk/pdbsum/2c6b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2c6b ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c6/2c6b_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c6/2c6b_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2c6b ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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</div>
</div>
<div class="pdbe-citations 2c6b" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2c6b" style="background-color:#fffaf0;"></div>
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==See Also==
 
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*[[MDM2|MDM2]]
 
== References ==
== References ==
<references/>
<references/>
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[[Category: Fersht, A R]]
[[Category: Fersht, A R]]
[[Category: Yu, G W]]
[[Category: Yu, G W]]
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[[Category: Alternative splicing]]
[[Category: Human mdm2]]
[[Category: Human mdm2]]
[[Category: Ligase]]
[[Category: Ligase]]
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[[Category: Proto- oncogene]]
[[Category: Proto- oncogene]]
[[Category: Ubl conjugation pathway]]
[[Category: Ubl conjugation pathway]]
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[[Category: Zinc]]
[[Category: Zinc finger]]
[[Category: Zinc finger]]

Revision as of 18:46, 24 January 2018

Solution structure of the C4 zinc-finger domain of HDM2

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