3g42
From Proteopedia
(Difference between revisions)
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==Crystal Structure of TACE with Tryptophan Sulfonamide Derivative Inhibitor== | ==Crystal Structure of TACE with Tryptophan Sulfonamide Derivative Inhibitor== | ||
<StructureSection load='3g42' size='340' side='right' caption='[[3g42]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='3g42' size='340' side='right' caption='[[3g42]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADAM17, CSVP, TACE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADAM17, CSVP, TACE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ADAM_17_endopeptidase ADAM 17 endopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.86 3.4.24.86] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ADAM_17_endopeptidase ADAM 17 endopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.86 3.4.24.86] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g42 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g42 OCA], [http://pdbe.org/3g42 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3g42 RCSB], [http://www.ebi.ac.uk/pdbsum/3g42 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g42 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g42 OCA], [http://pdbe.org/3g42 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3g42 RCSB], [http://www.ebi.ac.uk/pdbsum/3g42 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3g42 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g4/3g42_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g4/3g42_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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</div> | </div> | ||
<div class="pdbe-citations 3g42" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 3g42" style="background-color:#fffaf0;"></div> | ||
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| - | ==See Also== | ||
| - | *[[A Disintegrin And Metalloproteinase|A Disintegrin And Metalloproteinase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Aplasca, A]] | [[Category: Aplasca, A]] | ||
[[Category: Gopalsamy, A]] | [[Category: Gopalsamy, A]] | ||
| - | [[Category: K., Park]] | ||
[[Category: Levin, J I]] | [[Category: Levin, J I]] | ||
| + | [[Category: Park, K]] | ||
[[Category: Xu, W]] | [[Category: Xu, W]] | ||
[[Category: Zhang, Y H]] | [[Category: Zhang, Y H]] | ||
| + | [[Category: Alternative splicing]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
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[[Category: Notch signaling pathway]] | [[Category: Notch signaling pathway]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| + | [[Category: Polymorphism]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Sh3-binding]] | [[Category: Sh3-binding]] | ||
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[[Category: Tace/adam-17]] | [[Category: Tace/adam-17]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
| + | [[Category: Zinc]] | ||
[[Category: Zn-endopeptidase]] | [[Category: Zn-endopeptidase]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 19:18, 24 January 2018
Crystal Structure of TACE with Tryptophan Sulfonamide Derivative Inhibitor
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Categories: ADAM 17 endopeptidase | Human | Aplasca, A | Gopalsamy, A | Levin, J I | Park, K | Xu, W | Zhang, Y H | Alternative splicing | Cleavage on pair of basic residue | Glycoprotein | Hydrolase | Membrane | Metal-binding | Metalloprotease | Notch signaling pathway | Phosphoprotein | Polymorphism | Protease | Sh3-binding | Tace-inhibitor complex | Tace/adam-17 | Transmembrane | Zinc | Zn-endopeptidase | Zymogen
