This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5i4o

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
<StructureSection load='5i4o' size='340' side='right' caption='[[5i4o]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='5i4o' size='340' side='right' caption='[[5i4o]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5i4o]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I4O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5I4O FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5i4o]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I4O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5I4O FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=V28:N-({1-[2-(ACETYLAMINO)-2-DEOXY-BETA-D-GLUCOPYRANOSYL]-1H-1,2,3-TRIAZOL-4-YL}METHYL)-N-[([1,1-BIPHENYL]-4-YL)SULFONYL]-D-VALINE'>V28</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=V28:N-({1-[2-(ACETYLAMINO)-2-DEOXY-BETA-D-GLUCOPYRANOSYL]-1H-1,2,3-TRIAZOL-4-YL}METHYL)-N-[([1,1-BIPHENYL]-4-YL)SULFONYL]-D-VALINE'>V28</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5i3m|5i3m]], [[5i2z|5i2z]], [[5iol|5iol]], [[5i43|5i43]], [[5i12|5i12]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5i3m|5i3m]], [[5i2z|5i2z]], [[5iol|5iol]], [[5i43|5i43]], [[5i12|5i12]]</td></tr>
 +
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MMP12, HME ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5i4o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i4o OCA], [http://pdbe.org/5i4o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5i4o RCSB], [http://www.ebi.ac.uk/pdbsum/5i4o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5i4o ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5i4o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i4o OCA], [http://pdbe.org/5i4o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5i4o RCSB], [http://www.ebi.ac.uk/pdbsum/5i4o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5i4o ProSAT]</span></td></tr>
Line 24: Line 25:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Human]]
[[Category: Macrophage elastase]]
[[Category: Macrophage elastase]]
[[Category: Ciccone, L]]
[[Category: Ciccone, L]]

Revision as of 20:35, 24 January 2018

Crystal structure of the catalytic domain of MMP-12 in complex with a selective sugar-conjugated triazole-linked carboxylate zinc-chelator water-soluble inhibitor (DC28).

5i4o, resolution 2.05Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5i4o"
Personal tools