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2duu

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|PDB= 2duu |SIZE=350|CAPTION= <scene name='initialview01'>2duu</scene>, resolution 2.9&Aring;
|PDB= 2duu |SIZE=350|CAPTION= <scene name='initialview01'>2duu</scene>, resolution 2.9&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>
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|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(NADP(+))_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (NADP(+)) (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.13 1.2.1.13]
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(NADP(+))_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (NADP(+)) (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.13 1.2.1.13] </span>
|GENE=
|GENE=
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|DOMAIN=
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|RELATEDENTRY=[[2d2i|2D2I]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2duu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2duu OCA], [http://www.ebi.ac.uk/pdbsum/2duu PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2duu RCSB]</span>
}}
}}
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[[Category: Tamoi, M.]]
[[Category: Tamoi, M.]]
[[Category: Wada, K.]]
[[Category: Wada, K.]]
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[[Category: SO4]]
 
[[Category: apo-form]]
[[Category: apo-form]]
[[Category: glyceraldehyde 3-phosphate dehydrogenase]]
[[Category: glyceraldehyde 3-phosphate dehydrogenase]]
[[Category: rossmann fold]]
[[Category: rossmann fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:31:47 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:39:48 2008''

Revision as of 23:39, 30 March 2008


PDB ID 2duu

Drag the structure with the mouse to rotate
, resolution 2.9Å
Ligands:
Activity: Glyceraldehyde-3-phosphate dehydrogenase (NADP(+)) (phosphorylating), with EC number 1.2.1.13
Related: 2D2I


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Crystal Structure of apo-form of NADP-Dependent Glyceraldehyde-3-Phosphate Dehydrogenase from Synechococcus Sp.


Overview

The crystal structure of NADP-dependent apo-glyceraldehyde-3-phosphate dehydrogenase (apo-GAPDH) from Synechococcus PCC 7942 is reported. The crystal structure was solved by molecular replacement and refined to an R of 21.7% and R(free) of 27.5% at 2.9 angstroms resolution. The structural features of apo-GAPDH are as follows. The S-loop has an extremely flexible conformation and the sulfate ion is only taken into the classical P(i) site. A structural comparison with holo-GAPDHs indicated that the S-loop fixation is essential in the discrimination of NADP and NAD molecules.

About this Structure

2DUU is a Single protein structure of sequence from Synechococcus sp.. Full crystallographic information is available from OCA.

Reference

Structure of apo-glyceraldehyde-3-phosphate dehydrogenase from Synechococcus PCC7942., Kitatani T, Nakamura Y, Wada K, Kinoshita T, Tamoi M, Shigeoka S, Tada T, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Aug 1;62(Pt, 8):727-30. Epub 2006 Jul 29. PMID:16880542

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