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(→Crystal structure of the µ-opioid receptor bound to a morphinan antagonist)
(→Crystal structure of the µ-opioid receptor bound to a morphinan antagonist)
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Investigate the structure by dragging it around using your mouse or clicking the buttons below. Press SHIFT to zoom.
Investigate the structure by dragging it around using your mouse or clicking the buttons below. Press SHIFT to zoom.
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<jmol><jmollink><text>(a) Top view</text><script>SCRIPT http://proteopedia.org/wiki/images/f/fc/Nature10954_fig1c.spt('top')</script></jmollink></jmol>
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<jmol><jmollink><text>(a) exocellular view</text><script>SCRIPT http://proteopedia.org/wiki/images/f/fc/Nature10954_fig1c.spt('top')</script></jmollink></jmol>
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<jmol><jmollink><text>(b) Bottom view</text><script>SCRIPT http://proteopedia.org/wiki/images/f/fc/Nature10954_fig1c.spt('bottom')</script></jmollink></jmol>
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<jmol><jmollink><text>(b) endocellular</text><script>SCRIPT http://proteopedia.org/wiki/images/f/fc/Nature10954_fig1c.spt('bottom')</script></jmollink></jmol>
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<jmol><jmollink><text>(c) Side view</text><script>SCRIPT http://proteopedia.org/wiki/images/f/fc/Nature10954_fig1c.spt('side')</script></jmollink></jmol>
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<jmol><jmollink><text>(c) trans-membrane view</text><script>SCRIPT http://proteopedia.org/wiki/images/f/fc/Nature10954_fig1c.spt('side')</script></jmollink></jmol>
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<jmol><jmollink><text>(d) Side view with abstract membrane</text><script>SCRIPT http://proteopedia.org/wiki/images/f/fc/Nature10954_fig1c.spt('draw')</script></jmollink></jmol>
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<jmol><jmollink><text>(d) trans-membrane view with abstract membrane</text><script>SCRIPT http://proteopedia.org/wiki/images/f/fc/Nature10954_fig1c.spt('draw')</script></jmollink></jmol>
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Revision as of 02:31, 30 January 2018

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

Please note this way for referencing a paper using the PubmedID [1]. The full reference appears at the bottom of the page.

[https://www.nature.com/articles/nature10954 Nature volume 485, pages 321–326 (17 May 2012) doi:10.1038/nature10954]

Click a green link on the left to load Figure 1

Drag the structure with the mouse to rotate

/wiki/images/8/8b/4dkl-local-contact.png code for the above (space inserted just after the : <jmol><jmollink><text>View Figure 1a: Overall view of the µ-OR structure</text><script>exit;figure=1;SCRIPT "/wiki/images/8/8b/4dkl-local-contact.png"</script></jmollink></jmol>




is a close-up view of a bound to the µ-opioid receptor. The green circles indicate hydrogen bonds.
  1. ↑ Manglik A, Kruse AC, Kobilka TS, Thian FS, Mathiesen JM, Sunahara RK, Pardo L, Weis WI, Kobilka BK, Granier S. Crystal structure of the micro-opioid receptor bound to a morphinan antagonist. Nature. 2012 Mar 21. doi: 10.1038/nature10954. PMID:22437502 doi:10.1038/nature10954
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