1xpo

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==Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic bicyclomycin==
==Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic bicyclomycin==
<StructureSection load='1xpo' size='340' side='right' caption='[[1xpo]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
<StructureSection load='1xpo' size='340' side='right' caption='[[1xpo]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=BCM:BICYCLOMYCIN'>BCM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=BCM:BICYCLOMYCIN'>BCM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xpr|1xpr]], [[1xpu|1xpu]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xpr|1xpr]], [[1xpu|1xpu]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xpo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpo OCA], [http://pdbe.org/1xpo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xpo RCSB], [http://www.ebi.ac.uk/pdbsum/1xpo PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xpo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpo OCA], [http://pdbe.org/1xpo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xpo RCSB], [http://www.ebi.ac.uk/pdbsum/1xpo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xpo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xp/1xpo_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xp/1xpo_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xpo ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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</div>
</div>
<div class="pdbe-citations 1xpo" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1xpo" style="background-color:#fffaf0;"></div>
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==See Also==
 
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*[[Helicase|Helicase]]
 
== References ==
== References ==
<references/>
<references/>

Revision as of 06:33, 31 January 2018

Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic bicyclomycin

1xpo, resolution 3.15Å

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