2gs3

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==Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 4(GPX4)==
==Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 4(GPX4)==
<StructureSection load='2gs3' size='340' side='right' caption='[[2gs3]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='2gs3' size='340' side='right' caption='[[2gs3]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GPX4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GPX4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phospholipid-hydroperoxide_glutathione_peroxidase Phospholipid-hydroperoxide glutathione peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.12 1.11.1.12] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phospholipid-hydroperoxide_glutathione_peroxidase Phospholipid-hydroperoxide glutathione peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.12 1.11.1.12] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gs3 OCA], [http://pdbe.org/2gs3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gs3 RCSB], [http://www.ebi.ac.uk/pdbsum/2gs3 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gs3 OCA], [http://pdbe.org/2gs3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gs3 RCSB], [http://www.ebi.ac.uk/pdbsum/2gs3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2gs3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gs/2gs3_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gs/2gs3_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gs3 ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gs3 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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==See Also==
 
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*[[Glutathione peroxidase|Glutathione peroxidase]]
 
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Phospholipid-hydroperoxide glutathione peroxidase]]
[[Category: Phospholipid-hydroperoxide glutathione peroxidase]]
[[Category: Arrowsmith, C]]
[[Category: Arrowsmith, C]]
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[[Category: Delft, F Von]]
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[[Category: Delft, F von]]
[[Category: Edwards, A]]
[[Category: Edwards, A]]
[[Category: Gileadi, O]]
[[Category: Gileadi, O]]

Revision as of 06:38, 31 January 2018

Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 4(GPX4)

2gs3, resolution 1.90Å

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