2e2w
From Proteopedia
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|SITE= | |SITE= | ||
|LIGAND= | |LIGAND= | ||
- | |ACTIVITY= [http://en.wikipedia.org/wiki/DNA_ligase_(ATP) DNA ligase (ATP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.1 6.5.1.1] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_ligase_(ATP) DNA ligase (ATP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.1 6.5.1.1] </span> |
|GENE= LIG4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= LIG4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
+ | |DOMAIN= | ||
+ | |RELATEDENTRY= | ||
+ | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e2w OCA], [http://www.ebi.ac.uk/pdbsum/2e2w PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2e2w RCSB]</span> | ||
}} | }} | ||
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==Disease== | ==Disease== | ||
- | Known | + | Known disease associated with this structure: LIG4 syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601837 601837]], Multiple myeloma, resistance to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601837 601837]] |
==About this Structure== | ==About this Structure== | ||
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[[Category: xrcc4]] | [[Category: xrcc4]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:42:55 2008'' |
Revision as of 23:42, 30 March 2008
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Gene: | LIG4 (Homo sapiens) | ||||||
Activity: | DNA ligase (ATP), with EC number 6.5.1.1 | ||||||
Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
Coordinates: | save as pdb, mmCIF, xml |
Solution structure of the first BRCT domain of human DNA ligase IV
Disease
Known disease associated with this structure: LIG4 syndrome OMIM:[601837], Multiple myeloma, resistance to OMIM:[601837]
About this Structure
2E2W is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 02:42:55 2008
Categories: DNA ligase (ATP) | Homo sapiens | Single protein | Hayashi, F. | Nagashima, T. | RSGI, RIKEN Structural Genomics/Proteomics Initiative. | Yokoyama, S. | 3layers a/b/a | National project on protein structural and functional analyse | Non-homologous end jointing | Nppsfa | Parallel beta-sheet of 4 strand | Riken structural genomics/proteomics initiative | Rsgi | Structural genomic | V(d)j recombination | Xrcc4