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6bo7

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<StructureSection load='6bo7' size='340' side='right' caption='[[6bo7]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
<StructureSection load='6bo7' size='340' side='right' caption='[[6bo7]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6bo7]] is a 12 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=5hhu 5hhu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BO7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BO7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6bo7]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemamoeba_vivax Haemamoeba vivax]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=5hhu 5hhu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BO7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BO7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=YPG:[3-[(3~{R},4~{R})-3-(2-AZANYL-6-OXIDANYLIDENE-1~{H}-PURIN-9-YL)-4-[(2~{S})-2-OXIDANYL-2-PHOSPHONO-ETHOXY]PYRROLIDIN-1-YL]-3-OXIDANYLIDENE-PROPYL]PHOSPHONIC+ACID'>YPG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=YPG:[3-[(3~{R},4~{R})-3-(2-AZANYL-6-OXIDANYLIDENE-1~{H}-PURIN-9-YL)-4-[(2~{S})-2-OXIDANYL-2-PHOSPHONO-ETHOXY]PYRROLIDIN-1-YL]-3-OXIDANYLIDENE-PROPYL]PHOSPHONIC+ACID'>YPG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PVC01_080017300, PVP01_0812500, PVT01_080017400 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5855 Haemamoeba vivax])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hypoxanthine_phosphoribosyltransferase Hypoxanthine phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.8 2.4.2.8] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hypoxanthine_phosphoribosyltransferase Hypoxanthine phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.8 2.4.2.8] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bo7 OCA], [http://pdbe.org/6bo7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bo7 RCSB], [http://www.ebi.ac.uk/pdbsum/6bo7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bo7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bo7 OCA], [http://pdbe.org/6bo7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bo7 RCSB], [http://www.ebi.ac.uk/pdbsum/6bo7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bo7 ProSAT]</span></td></tr>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Haemamoeba vivax]]
[[Category: Hypoxanthine phosphoribosyltransferase]]
[[Category: Hypoxanthine phosphoribosyltransferase]]
[[Category: Guddat, L W]]
[[Category: Guddat, L W]]

Revision as of 07:12, 31 January 2018

Crystal structure of Plasmodium vivax hypoxanthine guanine phosphoribosyltransferase in complex with [3R,4R]-4-guanin-9-yl-3-((S)-2-hydroxy-2-phosphonoethyl)oxy-1-N-(phosphonopropionyl)pyrrolidine

6bo7, resolution 2.86Å

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