6btk
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6btk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6btk OCA], [http://pdbe.org/6btk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6btk RCSB], [http://www.ebi.ac.uk/pdbsum/6btk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6btk ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6btk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6btk OCA], [http://pdbe.org/6btk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6btk RCSB], [http://www.ebi.ac.uk/pdbsum/6btk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6btk ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The atomic structure of the infectious, protease-resistant, beta-sheet-rich and fibrillar mammalian prion remains unknown. Through the cryo-EM method MicroED, we reveal the sub-angstrom-resolution structure of a protofibril formed by a wild-type segment from the beta2-alpha2 loop of the bank vole prion protein. The structure of this protofibril reveals a stabilizing network of hydrogen bonds that link polar zippers within a sheet, producing motifs we have named 'polar clasps'. | ||
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| + | Sub-angstrom cryo-EM structure of a prion protofibril reveals a polar clasp.,Gallagher-Jones M, Glynn C, Boyer DR, Martynowycz MW, Hernandez E, Miao J, Zee CT, Novikova IV, Goldschmidt L, McFarlane HT, Helguera GF, Evans JE, Sawaya MR, Cascio D, Eisenberg DS, Gonen T, Rodriguez JA Nat Struct Mol Biol. 2018 Jan 15. pii: 10.1038/s41594-017-0018-0. doi:, 10.1038/s41594-017-0018-0. PMID:29335561<ref>PMID:29335561</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 6btk" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 07:12, 31 January 2018
Segment from bank vole prion protein 168-176 QYNNQNNFV
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