2ea3
From Proteopedia
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|PDB= 2ea3 |SIZE=350|CAPTION= <scene name='initialview01'>2ea3</scene>, resolution 1.78Å | |PDB= 2ea3 |SIZE=350|CAPTION= <scene name='initialview01'>2ea3</scene>, resolution 1.78Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene> | + | |LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ea3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ea3 OCA], [http://www.ebi.ac.uk/pdbsum/2ea3 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ea3 RCSB]</span> | ||
}} | }} | ||
| Line 24: | Line 27: | ||
[[Category: Bott, R.]] | [[Category: Bott, R.]] | ||
[[Category: Shaw, A.]] | [[Category: Shaw, A.]] | ||
| - | [[Category: SO4]] | ||
[[Category: celloulomona]] | [[Category: celloulomona]] | ||
[[Category: chymotrypsin]] | [[Category: chymotrypsin]] | ||
[[Category: protease]] | [[Category: protease]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:45:59 2008'' |
Revision as of 23:46, 30 March 2008
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| , resolution 1.78Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal Structure Of Cellulomonas Bogoriensis Chymotrypsin
Overview
The crystal structure of a secreted chymotrypsin from the alkaliphile Cellulomonas bogoriensis has been determined using data to 1.78 A resolution and refined to a crystallographic R factor of 0.167. The crystal structure reveals a large P1 substrate-specificity pocket, as expected for chymotrypsins. The structure is compared with close structural homologues. This comparison does not reveal clear reasons for the alkali tolerance of the enzyme, but the greater compactness of the structure and lowered hydrogen bonding may play a role.
About this Structure
2EA3 is a Protein complex structure of sequences from Cellulomonas bogoriensis. Full crystallographic information is available from OCA.
Reference
Structure determination and analysis of a bacterial chymotrypsin from Cellulomonas bogoriensis., Shaw A, Saldajeno ML, Kolkman MA, Jones BE, Bott R, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Apr 1;63(Pt, 4):266-9. Epub 2007 Mar 23. PMID:17401191
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