6bkj
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Human Calpain-3 Protease Core in Complex with Leupeptin== | |
| - | + | <StructureSection load='6bkj' size='340' side='right' caption='[[6bkj]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6bkj]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BKJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BKJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=AR7:AMINO{[(4S)-4-AMINO-5,5-DIHYDROXYPENTYL]AMINO}METHANIMINIUM'>AR7</scene></td></tr> |
| - | [[Category: Davies, P | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6bjd|6bjd]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calpain-3 Calpain-3], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.54 3.4.22.54] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bkj OCA], [http://pdbe.org/6bkj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bkj RCSB], [http://www.ebi.ac.uk/pdbsum/6bkj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bkj ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/CAN3_HUMAN CAN3_HUMAN]] Autosomal recessive limb girdle muscular dystrophy type 2A. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CAN3_HUMAN CAN3_HUMAN]] Calcium-regulated non-lysosomal thiol-protease. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Calpain-3]] | ||
| + | [[Category: Campbell, R L]] | ||
| + | [[Category: Davies, P L]] | ||
[[Category: Ye, Q]] | [[Category: Ye, Q]] | ||
| - | [[Category: | + | [[Category: Calcium binding]] |
| + | [[Category: Calpain]] | ||
| + | [[Category: Complex]] | ||
| + | [[Category: Cysteine protease]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: P94]] | ||
Revision as of 06:19, 7 February 2018
Crystal Structure of Human Calpain-3 Protease Core in Complex with Leupeptin
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