6bsz
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Human mGlu8 Receptor complexed with glutamate== | |
| - | + | <StructureSection load='6bsz' size='340' side='right' caption='[[6bsz]], [[Resolution|resolution]] 2.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6bsz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BSZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BSZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GGL:GAMMA-L-GLUTAMIC+ACID'>GGL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bsz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bsz OCA], [http://pdbe.org/6bsz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bsz RCSB], [http://www.ebi.ac.uk/pdbsum/6bsz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bsz ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GRM8_HUMAN GRM8_HUMAN]] G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.<ref>PMID:9473604</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Atwell, S]] | ||
| + | [[Category: Chen, Q]] | ||
| + | [[Category: Hao, J]] | ||
| + | [[Category: Ho, J D]] | ||
| + | [[Category: Monn, J A]] | ||
| + | [[Category: Schkeryantz, J M]] | ||
| + | [[Category: Vargas, M C]] | ||
| + | [[Category: Wang, J]] | ||
| + | [[Category: Zhang, A]] | ||
| + | [[Category: Gene id: 2918]] | ||
| + | [[Category: Glutamate]] | ||
| + | [[Category: Grm8]] | ||
| + | [[Category: Mglur8]] | ||
| + | [[Category: Signaling protein]] | ||
Revision as of 06:20, 7 February 2018
Human mGlu8 Receptor complexed with glutamate
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Categories: Atwell, S | Chen, Q | Hao, J | Ho, J D | Monn, J A | Schkeryantz, J M | Vargas, M C | Wang, J | Zhang, A | Gene id: 2918 | Glutamate | Grm8 | Mglur8 | Signaling protein
