2eb8
From Proteopedia
| Line 4: | Line 4: | ||
|PDB= 2eb8 |SIZE=350|CAPTION= <scene name='initialview01'>2eb8</scene>, resolution 1.65Å | |PDB= 2eb8 |SIZE=350|CAPTION= <scene name='initialview01'>2eb8</scene>, resolution 1.65Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= | + | |LIGAND= <scene name='pdbligand=CUP:(N-SALICYLIDEN-L-PHENYLALANATO)-COPPER(II)'>CUP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[2eb9|2EB9]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eb8 OCA], [http://www.ebi.ac.uk/pdbsum/2eb8 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2eb8 RCSB]</span> | ||
}} | }} | ||
| Line 29: | Line 32: | ||
[[Category: Watanabe, Y.]] | [[Category: Watanabe, Y.]] | ||
[[Category: Yamane, T.]] | [[Category: Yamane, T.]] | ||
| - | [[Category: CUP]] | ||
| - | [[Category: PO4]] | ||
[[Category: oxygen storage/transport]] | [[Category: oxygen storage/transport]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:46:28 2008'' |
Revision as of 23:46, 30 March 2008
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| , resolution 1.65Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||
| Related: | 2EB9
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal Structure of Cu(II)(Sal-Phe)/apo-Myoglobin
Overview
apo-Myoglobin (apo-Mb) was reconstituted with three copper complexes: CuII(Sal-Phe) (1; Sal-Phe = N-salicylidene-L-phenylalanato), CuII(Sal-Leu) (2; Sal-Leu = N-salicylidene-L-leucinato), and CuII(Sal-Ala) (3; Sal-Ala = N-salicylidene-L-alanato). The crystal structures of 1.apo-Mb (1.65 Angstrom resolution) and 2.apo-Mb (1.8 Angstrom resolution) show that the coordination geometry around the CuII atom in apo-Mb is distorted square-planar with tridentate Sal-X and a Nepsilon atom of His64 in the apo-Mb cavity and the plane of these copper complexes is perpendicular to that of heme. These results suggest that the apo-Mb cavity can hold metal complexes with various coordination geometries.
About this Structure
2EB8 is a Single protein structure of sequence from Physeter catodon. Full crystallographic information is available from OCA.
Reference
Design and structure analysis of artificial metalloproteins: selective coordination of His64 to copper complexes with square-planar structure in the apo-myoglobin scaffold., Abe S, Ueno T, Reddy PA, Okazaki S, Hikage T, Suzuki A, Yamane T, Nakajima H, Watanabe Y, Inorg Chem. 2007 Jun 25;46(13):5137-9. Epub 2007 May 25. PMID:17523632
Page seeded by OCA on Mon Mar 31 02:46:28 2008
