5muc
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of the FimH lectin domain in complex with 1,5-Anhydromannitol== | |
- | + | <StructureSection load='5muc' size='340' side='right' caption='[[5muc]], [[Resolution|resolution]] 2.60Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[5muc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MUC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MUC FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AH2:1,5-Anhydromannitol'>AH2</scene></td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5muc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5muc OCA], [http://pdbe.org/5muc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5muc RCSB], [http://www.ebi.ac.uk/pdbsum/5muc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5muc ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Ernst, B]] | ||
+ | [[Category: Jakob, R P]] | ||
+ | [[Category: Maier, T]] | ||
+ | [[Category: Rabbani, S]] | ||
+ | [[Category: Bladder infection]] | ||
+ | [[Category: Carbohydrate]] | ||
+ | [[Category: Fimh]] | ||
+ | [[Category: Lectin]] | ||
+ | [[Category: Sugar binding protein]] | ||
+ | [[Category: Upec]] | ||
+ | [[Category: Uti]] |
Revision as of 06:21, 15 February 2018
Crystal structure of the FimH lectin domain in complex with 1,5-Anhydromannitol
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Categories: Ernst, B | Jakob, R P | Maier, T | Rabbani, S | Bladder infection | Carbohydrate | Fimh | Lectin | Sugar binding protein | Upec | Uti