5muc

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'''Unreleased structure'''
 
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The entry 5muc is ON HOLD until Paper Publication
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==Crystal structure of the FimH lectin domain in complex with 1,5-Anhydromannitol==
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<StructureSection load='5muc' size='340' side='right' caption='[[5muc]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5muc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MUC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MUC FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AH2:1,5-Anhydromannitol'>AH2</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5muc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5muc OCA], [http://pdbe.org/5muc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5muc RCSB], [http://www.ebi.ac.uk/pdbsum/5muc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5muc ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.
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__TOC__
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</StructureSection>
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[[Category: Ernst, B]]
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[[Category: Jakob, R P]]
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[[Category: Maier, T]]
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[[Category: Rabbani, S]]
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[[Category: Bladder infection]]
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[[Category: Carbohydrate]]
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[[Category: Fimh]]
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[[Category: Lectin]]
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[[Category: Sugar binding protein]]
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[[Category: Upec]]
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[[Category: Uti]]

Revision as of 06:21, 15 February 2018

Crystal structure of the FimH lectin domain in complex with 1,5-Anhydromannitol

5muc, resolution 2.60Å

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