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6eih

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'''Unreleased structure'''
 
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The entry 6eih is ON HOLD until Paper Publication
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==The crystal structure of 14-3-3 epsilon in complex with the phosphorylated NELFE peptide==
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<StructureSection load='6eih' size='340' side='right' caption='[[6eih]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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Authors: Akutsu, M., Wagner, S.A., Beli, P.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6eih]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EIH FirstGlance]. <br>
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Description: The crystal structure of 14-3-3 epsilon in complex with the phosphorylated NELFE peptide
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6eih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6eih OCA], [http://pdbe.org/6eih PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6eih RCSB], [http://www.ebi.ac.uk/pdbsum/6eih PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6eih ProSAT]</span></td></tr>
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[[Category: Wagner, S.A]]
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</table>
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== Disease ==
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[[http://www.uniprot.org/uniprot/1433E_HUMAN 1433E_HUMAN]] Distal 17p13.3 microdeletion syndrome;17p13.3 microduplication syndrome;Miller-Dieker syndrome.
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== Function ==
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[[http://www.uniprot.org/uniprot/1433E_HUMAN 1433E_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
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__TOC__
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</StructureSection>
[[Category: Akutsu, M]]
[[Category: Akutsu, M]]
[[Category: Beli, P]]
[[Category: Beli, P]]
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[[Category: Wagner, S A]]
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[[Category: 14-3-3]]
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[[Category: Nelf]]
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[[Category: Protein binding]]

Revision as of 06:36, 15 February 2018

The crystal structure of 14-3-3 epsilon in complex with the phosphorylated NELFE peptide

6eih, resolution 2.70Å

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