This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6ffz
From Proteopedia
(Difference between revisions)
m (Protected "6ffz" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of R. ruber ADH-A, mutant F43H, Y54L== | |
| + | <StructureSection load='6ffz' size='340' side='right' caption='[[6ffz]], [[Resolution|resolution]] 1.71Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6ffz]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FFZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FFZ FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ffz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ffz OCA], [http://pdbe.org/6ffz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ffz RCSB], [http://www.ebi.ac.uk/pdbsum/6ffz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ffz ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Laboratory evolution of alcohol dehydrogenase produced enzyme variants with improved turnover numbers with a vicinal 1,2-diol and its corresponding hydroxyketone. Crystal structure and transient kinetics analysis aids in rationalizing the new functions of these variants. | ||
| - | + | Directed Evolution of Alcohol Dehydrogenase for Improved Stereoselective Redox Transformations of 1-Phenylethane-1,2-diol and Its Corresponding Acyloin.,Hamnevik E, Maurer D, Enugala TR, Chu T, Lofgren R, Dobritzsch D, Widersten M Biochemistry. 2018 Feb 2. doi: 10.1021/acs.biochem.8b00055. PMID:29384657<ref>PMID:29384657</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| + | <div class="pdbe-citations 6ffz" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Dobritzsch, D]] | [[Category: Dobritzsch, D]] | ||
| + | [[Category: Enugala, T R]] | ||
[[Category: Hamnevik, E]] | [[Category: Hamnevik, E]] | ||
| - | [[Category: Widersten, M]] | ||
| - | [[Category: Enugala, T.R]] | ||
[[Category: Maurer, D]] | [[Category: Maurer, D]] | ||
| + | [[Category: Widersten, M]] | ||
| + | [[Category: Alcohol dehydrogenase mutant variant]] | ||
| + | [[Category: Nadh-dependent]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Rossmann fold]] | ||
| + | [[Category: Zn2+-dependent]] | ||
Revision as of 06:37, 15 February 2018
Crystal structure of R. ruber ADH-A, mutant F43H, Y54L
| |||||||||||
