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==Structural Basis for 3-deoxy-CDCA Binding and Activation of FXR==
==Structural Basis for 3-deoxy-CDCA Binding and Activation of FXR==
<StructureSection load='1ot7' size='340' side='right' caption='[[1ot7]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='1ot7' size='340' side='right' caption='[[1ot7]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1osv|1osv]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1osv|1osv]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NR1H4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NR1H4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ot7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ot7 OCA], [http://pdbe.org/1ot7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ot7 RCSB], [http://www.ebi.ac.uk/pdbsum/1ot7 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ot7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ot7 OCA], [http://pdbe.org/1ot7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ot7 RCSB], [http://www.ebi.ac.uk/pdbsum/1ot7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ot7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ot/1ot7_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ot/1ot7_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 1ot7" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1ot7" style="background-color:#fffaf0;"></div>
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==See Also==
 
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*[[Bile acid receptor|Bile acid receptor]]
 
== References ==
== References ==
<references/>
<references/>

Revision as of 07:51, 15 February 2018

Structural Basis for 3-deoxy-CDCA Binding and Activation of FXR

1ot7, resolution 2.90Å

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