Thyroid hormone receptor
From Proteopedia
(Difference between revisions)
(New page: <StructureSection load='1xzx' size='350' side='right' caption='Structure of human thyroid hormone receptor ligand-binding domain complex with thyroid hormone and cacodylate (PDB entry [[1x...) |
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**[[4lnwx]] – hTR a1 LBD + triiodo-thyronine + tetraiodo-thyronine <br /> | **[[4lnwx]] – hTR a1 LBD + triiodo-thyronine + tetraiodo-thyronine <br /> | ||
**[[3hzf]], [[3ilz]], [[3jzb]] – hTR a1 LBD + thyromimetic<br /> | **[[3hzf]], [[3ilz]], [[3jzb]] – hTR a1 LBD + thyromimetic<br /> | ||
| - | [[3uvv]] – hTR a1 LBD + retinoic acid receptor + retinoic acid + triiodo-thyronine <br /> | + | **[[3uvv]] – hTR a1 LBD + retinoic acid receptor + retinoic acid + triiodo-thyronine <br /> |
*Thyroid hormone receptor β1 LBD residues 202-461 | *Thyroid hormone receptor β1 LBD residues 202-461 | ||
**[[1nq2]], [[1nuo]], [[1nq0]], [[1nq1]], [[3d57]] – hTR b1 LBD (mutant) + triiodothyroacetic acid<br /> | **[[1nq2]], [[1nuo]], [[1nq0]], [[1nq1]], [[3d57]] – hTR b1 LBD (mutant) + triiodothyroacetic acid<br /> | ||
| - | [[1q4x]] – hTR b1 LBD + agonist <br /> | + | **[[1q4x]] – hTR b1 LBD + agonist <br /> |
**[[1xzx]], [[1y0x]], [[3gws]] – hTR b1 LBD + triiodo-thyronine <br /> | **[[1xzx]], [[1y0x]], [[3gws]] – hTR b1 LBD + triiodo-thyronine <br /> | ||
| - | [[1r6g]], [[3imy]], [[3jzc]], [[1n46]] – hTR b1 LBD + thyromimetic<br /> | + | **[[1r6g]], [[3imy]], [[3jzc]], [[1n46]] – hTR b1 LBD + thyromimetic<br /> |
| - | [[1nax]] – hTR b1 LBD + ligand<br /> | + | **[[1nax]] – hTR b1 LBD + ligand<br /> |
| - | [[2pin]], [[2j4a]] – hTR b1 LBD + inhibitor<br /> | + | **[[2pin]], [[2j4a]] – hTR b1 LBD + inhibitor<br /> |
**[[1bsx]] – hTR b1 LBD + GRIP1 peptide <br /> | **[[1bsx]] – hTR b1 LBD + GRIP1 peptide <br /> | ||
**[[4zo1]] – hTR b1 LBD + retinoic acid receptor + NCOA2 peptide + triiodo-thyronine <br /> | **[[4zo1]] – hTR b1 LBD + retinoic acid receptor + NCOA2 peptide + triiodo-thyronine <br /> | ||
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*Thyroid hormone receptor β1 DBD residues 104-201 | *Thyroid hormone receptor β1 DBD residues 104-201 | ||
| - | [[3m9e]] – hTR b1 DBD + DNA<br /> | + | **[[3m9e]] – hTR b1 DBD + DNA<br /> |
| - | [[2nll]] – hTR b1 DBD + retinoic acid receptor + DNA<br /> | + | **[[2nll]] – hTR b1 DBD + retinoic acid receptor + DNA<br /> |
}} | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 11:08, 19 February 2018
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3D Structures of thyroid hormone receptor
Updated on 19-February-2018
References
- ↑ Forrest D, Erway LC, Ng L, Altschuler R, Curran T. Thyroid hormone receptor beta is essential for development of auditory function. Nat Genet. 1996 Jul;13(3):354-7. doi: 10.1038/ng0796-354. PMID:8673137 doi:http://dx.doi.org/10.1038/ng0796-354
- ↑ Cheng SY. Thyroid hormone receptor mutations and disease: beyond thyroid hormone resistance. Trends Endocrinol Metab. 2005 May-Jun;16(4):176-82. doi:, 10.1016/j.tem.2005.03.008. PMID:15860414 doi:http://dx.doi.org/10.1016/j.tem.2005.03.008
- ↑ Kim WG, Cheng SY. Thyroid hormone receptors and cancer. Biochim Biophys Acta. 2013 Jul;1830(7):3928-36. doi:, 10.1016/j.bbagen.2012.04.002. Epub 2012 Apr 6. PMID:22507269 doi:http://dx.doi.org/10.1016/j.bbagen.2012.04.002
- ↑ Kunitake JM, Hartman N, Henson LC, Lieberman J, Williams DE, Wong M, Hershman JM. 3,5,3'-triiodothyroacetic acid therapy for thyroid hormone resistance. J Clin Endocrinol Metab. 1989 Aug;69(2):461-6. doi: 10.1210/jcem-69-2-461. PMID:2753985 doi:http://dx.doi.org/10.1210/jcem-69-2-461
