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==Structure== | ==Structure== | ||
<StructureSection load='1xmi' size='340' side='right' caption='Caption for this structure' scene=''> | <StructureSection load='1xmi' size='340' side='right' caption='Caption for this structure' scene=''> | ||
| - | Composed of 1480 amino acids in 5 domains, each connected by a nucleotide binding domain. There are 6 alpha helices and 2 trans-membrane domains. | + | Composed of 1480 amino acids in 5 domains, each connected by a nucleotide binding domain. There are 6 alpha helices and 2 trans-membrane domains. It has 27 exons, 26 introns, and it is a glycoprotein. |
== Function == | == Function == | ||
The protein regulates transport of bicarbonate and chloride ions. Important for fluid and osmotic homeostasis. The Chloride channel only opens when the R domain is phosphorylated. It also protects against pathogens by regulation the pH of airway surfaces. | The protein regulates transport of bicarbonate and chloride ions. Important for fluid and osmotic homeostasis. The Chloride channel only opens when the R domain is phosphorylated. It also protects against pathogens by regulation the pH of airway surfaces. | ||
Revision as of 21:09, 21 February 2018
| This Sandbox is Reserved from January through July 31, 2018 for use in the course HLSC322: Principles of Genetics and Genomics taught by Genevieve Houston-Ludlam at the University of Maryland, College Park, USA. This reservation includes Sandbox Reserved 1311 through Sandbox Reserved 1430. |
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Structure
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References
protein
