5h7l
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Complex of Elongation factor 2-50S ribosomal protein L12== | |
| - | + | <StructureSection load='5h7l' size='340' side='right' caption='[[5h7l]], [[Resolution|resolution]] 3.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5h7l]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H7L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5H7L FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GCP:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>GCP</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5h7j|5h7j]], [[5h7k|5h7k]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5h7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5h7l OCA], [http://pdbe.org/5h7l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5h7l RCSB], [http://www.ebi.ac.uk/pdbsum/5h7l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5h7l ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RL12_PYRHO RL12_PYRHO]] Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. The stalk complex of P.horikoshii binds to E.coli large subunits and confers on them the ability to interact with eukaryotic elongation factors. Each succesive L12 dimer bound along the P0 spine increases the GTPase activity of elongation factors and increases translation by reconsituted ribosomes.<ref>PMID:17804412</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Kato, K]] | ||
| + | [[Category: Tanzawa, T]] | ||
| + | [[Category: Uchiumi, T]] | ||
| + | [[Category: Yao, M]] | ||
| + | [[Category: Elongation factor]] | ||
| + | [[Category: Gtp-binding]] | ||
| + | [[Category: Protein biosynthesis]] | ||
| + | [[Category: Translation-ribosomal protein complex]] | ||
Revision as of 07:08, 22 February 2018
Complex of Elongation factor 2-50S ribosomal protein L12
| |||||||||||
