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5mdl
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of an O2-tolerant [NiFe]-hydrogenase from Ralstonia eutropha in its O2-derivatized form by a "soak-and-freeze" derivatization method== | |
| - | + | <StructureSection load='5mdl' size='340' side='right' caption='[[5mdl]], [[Resolution|resolution]] 1.41Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5mdl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MDL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MDL FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene>, <scene name='pdbligand=F4S:FE4-S3+CLUSTER'>F4S</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NFV:NI-FE+OXIDIZED+ACTIVE+CENTER'>NFV</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydrogenase_(acceptor) Hydrogenase (acceptor)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.12.99.6 1.12.99.6] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mdl OCA], [http://pdbe.org/5mdl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mdl RCSB], [http://www.ebi.ac.uk/pdbsum/5mdl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mdl ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MBHL_CUPNH MBHL_CUPNH]] This enzyme recycles the H(2) produced by nitrogenase to increase the production of ATP and to protect nitrogenase against inhibition or damage by O(2) under carbon- or phosphate-limited conditions. [[http://www.uniprot.org/uniprot/MBHS_CUPNH MBHS_CUPNH]] This enzyme recycles the H(2) produced by nitrogenase to increase the production of ATP and to protect nitrogenase against inhibition or damage by O(2) under carbon- or phosphate-limited conditions. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Kalms, J]] | ||
[[Category: Scheerer, P]] | [[Category: Scheerer, P]] | ||
| - | [[Category: Kalms, J]] | ||
[[Category: Schmidt, A]] | [[Category: Schmidt, A]] | ||
| + | [[Category: Aerobic hydrogen bacteria]] | ||
| + | [[Category: Bimetallic]] | ||
| + | [[Category: Dehydrogenase]] | ||
| + | [[Category: Dihydrogen]] | ||
| + | [[Category: Fe-s cluster]] | ||
| + | [[Category: Gas transport]] | ||
| + | [[Category: Hydrogen catalysis]] | ||
| + | [[Category: Hydrophobic tunnel]] | ||
| + | [[Category: Knallgasbacteria]] | ||
| + | [[Category: Membrane]] | ||
| + | [[Category: Membrane bound]] | ||
| + | [[Category: Metalloenzyme]] | ||
| + | [[Category: Metalloprotein catalytic center]] | ||
| + | [[Category: Ni-fe active site]] | ||
| + | [[Category: Oxidized state]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Oxygen derivatisation]] | ||
| + | [[Category: Oxygen derivatised state]] | ||
| + | [[Category: Oxygen tolerant hydrogenase]] | ||
| + | [[Category: Proteobacteria]] | ||
| + | [[Category: T-cluster]] | ||
Revision as of 07:09, 22 February 2018
Crystal structure of an O2-tolerant [NiFe]-hydrogenase from Ralstonia eutropha in its O2-derivatized form by a "soak-and-freeze" derivatization method
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Categories: Kalms, J | Scheerer, P | Schmidt, A | Aerobic hydrogen bacteria | Bimetallic | Dehydrogenase | Dihydrogen | Fe-s cluster | Gas transport | Hydrogen catalysis | Hydrophobic tunnel | Knallgasbacteria | Membrane | Membrane bound | Metalloenzyme | Metalloprotein catalytic center | Ni-fe active site | Oxidized state | Oxidoreductase | Oxygen derivatisation | Oxygen derivatised state | Oxygen tolerant hydrogenase | Proteobacteria | T-cluster
