6bw5
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Human GPT (DPAGT1) in complex with tunicamycin== | |
| - | + | <StructureSection load='6bw5' size='340' side='right' caption='[[6bw5]], [[Resolution|resolution]] 3.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6bw5]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BW5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BW5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PGW:(1R)-2-{[(S)-{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(HEXADECANOYLOXY)METHYL]ETHYL+(9Z)-OCTADEC-9-ENOATE'>PGW</scene>, <scene name='pdbligand=TUM:TUNICAMYCIN'>TUM</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine--dolichyl-phosphate_N-acetylglucosaminephosphotransferase UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.8.15 2.7.8.15] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bw5 OCA], [http://pdbe.org/6bw5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bw5 RCSB], [http://www.ebi.ac.uk/pdbsum/6bw5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bw5 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/GPT_HUMAN GPT_HUMAN]] DPAGT1-CDG;Congenital myasthenic syndromes with glycosylation defect. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GPT_HUMAN GPT_HUMAN]] Catalyzes the initial step in the synthesis of dolichol-P-P-oligosaccharides. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase]] | ||
| + | [[Category: Kuk, A C.Y]] | ||
| + | [[Category: Lee, S Y]] | ||
| + | [[Category: Mashalidis, E H]] | ||
| + | [[Category: Yoo, J]] | ||
| + | [[Category: Endoplasmic reticulum]] | ||
| + | [[Category: N-linked glycosylation]] | ||
| + | [[Category: Natural product]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Transferase-antibiotic complex]] | ||
| + | [[Category: Tunicamycin]] | ||
Revision as of 07:28, 22 February 2018
Human GPT (DPAGT1) in complex with tunicamycin
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