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2es4
From Proteopedia
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|PDB= 2es4 |SIZE=350|CAPTION= <scene name='initialview01'>2es4</scene>, resolution 1.85Å | |PDB= 2es4 |SIZE=350|CAPTION= <scene name='initialview01'>2es4</scene>, resolution 1.85Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> | + | |LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/Triacylglycerol_lipase Triacylglycerol lipase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.3 3.1.1.3] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Triacylglycerol_lipase Triacylglycerol lipase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.3 3.1.1.3] </span> |
|GENE= lifO, lipB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=337 Burkholderia glumae]) | |GENE= lifO, lipB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=337 Burkholderia glumae]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[1cvl|1CVL]], [[1tah|1TAH]], [[1qge|1QGE]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2es4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2es4 OCA], [http://www.ebi.ac.uk/pdbsum/2es4 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2es4 RCSB]</span> | ||
}} | }} | ||
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[[Category: Tommassen, J.]] | [[Category: Tommassen, J.]] | ||
[[Category: Wyns, L.]] | [[Category: Wyns, L.]] | ||
| - | [[Category: CA]] | ||
| - | [[Category: IOD]] | ||
[[Category: a/b hydrolase fold]] | [[Category: a/b hydrolase fold]] | ||
[[Category: all alpha helix protein]] | [[Category: all alpha helix protein]] | ||
| Line 37: | Line 38: | ||
[[Category: triacylglycerol hydrolase]] | [[Category: triacylglycerol hydrolase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:53:04 2008'' |
Revision as of 23:53, 30 March 2008
| |||||||
| , resolution 1.85Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , | ||||||
| Gene: | lifO, lipB (Burkholderia glumae) | ||||||
| Activity: | Triacylglycerol lipase, with EC number 3.1.1.3 | ||||||
| Related: | 1CVL, 1TAH, 1QGE
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of the Burkholderia glumae lipase-specific foldase in complex with its cognate lipase
Overview
Secretion via the type II secretion pathway in Gram-negative bacteria often relies crucially on steric chaperones in the periplasm. Here, we report the crystal structure of the soluble form of a lipase-specific foldase (Lif) from Burkholderia glumae in complex with its cognate lipase. The structure reveals how Lif uses a novel alpha-helical scaffold to embrace lipase, thereby creating an unusually extensive folding platform.
About this Structure
2ES4 is a Protein complex structure of sequences from Burkholderia glumae. Full crystallographic information is available from OCA.
Reference
Structure of a membrane-based steric chaperone in complex with its lipase substrate., Pauwels K, Lustig A, Wyns L, Tommassen J, Savvides SN, Van Gelder P, Nat Struct Mol Biol. 2006 Apr;13(4):374-5. Epub 2006 Mar 5. PMID:16518399
Page seeded by OCA on Mon Mar 31 02:53:04 2008
