5qc7
From Proteopedia
(Difference between revisions)
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<StructureSection load='5qc7' size='340' side='right' caption='[[5qc7]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='5qc7' size='340' side='right' caption='[[5qc7]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5qc7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QC7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QC7 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5qc7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QC7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QC7 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BQS:2-[1-(cyclohexylmethyl)piperidin-4-yl]-1-{3-[3-{[2-(piperidin-1-yl)ethyl]sulfanyl}-4-(trifluoromethyl)phenyl]-1-propyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl}ethan-1-one'>BQS</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EOH:ETHANOL'>EOH</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BQS:2-[1-(cyclohexylmethyl)piperidin-4-yl]-1-{3-[3-{[2-(piperidin-1-yl)ethyl]sulfanyl}-4-(trifluoromethyl)phenyl]-1-propyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl}ethan-1-one'>BQS</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EOH:ETHANOL'>EOH</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CTSS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qc7 OCA], [http://pdbe.org/5qc7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qc7 RCSB], [http://www.ebi.ac.uk/pdbsum/5qc7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qc7 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qc7 OCA], [http://pdbe.org/5qc7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qc7 RCSB], [http://www.ebi.ac.uk/pdbsum/5qc7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qc7 ProSAT]</span></td></tr> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Cathepsin S]] | [[Category: Cathepsin S]] | ||
| + | [[Category: Human]] | ||
[[Category: Ameriks, M K]] | [[Category: Ameriks, M K]] | ||
[[Category: Bembenek, S D]] | [[Category: Bembenek, S D]] | ||
Revision as of 08:19, 22 February 2018
Crystal structure of human Cathepsin-S with bound ligand
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Categories: Cathepsin S | Human | Ameriks, M K | Bembenek, S D | Burley, S K | Mirzadegan, T | Shao, C | Yang, H | Cathepsin s | D3r | Hydrolase | Ligand docking
