Sandbox Reserved 1392
From Proteopedia
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{{Sandbox_Reserved_HLSC322}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | {{Sandbox_Reserved_HLSC322}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | ||
| - | == | + | ==DNA Structure== |
| - | <StructureSection load=' | + | <StructureSection load='2o72' size='340' side='right' caption='Caption for this structure' scene=''> |
This is a default text for your page ''''''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | This is a default text for your page ''''''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
== Function == | == Function == | ||
| - | Epithelial-cadherin (1-213), or E-cadherin, is a calcium-dependent cell adhesion protein. E-cadherin help regulate bacterial interaction with mammalian tissues and play a key role in blastula formation. | ||
== Disease == | == Disease == | ||
| - | E-cadherin is a tumor suppressor gene. Degradation or loss of function of the gene is thought to be linked to metastasis and proliferation of tumors. In particular, mutations in the E-cadherin gene are linked to a series of cancers, including gastric, breast, colorectal, ovarian, and thyroid cancers. | ||
== Relevance == | == Relevance == | ||
== Structural highlights == | == Structural highlights == | ||
| - | + | <scene name='77/777712/Backbone_of_molecule/1'>Back bone of E-cadherin</scene> | |
| - | + | DNA is made up of <scene name='77/777712/Base_pairs_of_dna/1'>[[base pairs]</scene>]. | |
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
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</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
| - | + | <references/> | |
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Revision as of 21:42, 22 February 2018
| This Sandbox is Reserved from January through July 31, 2018 for use in the course HLSC322: Principles of Genetics and Genomics taught by Genevieve Houston-Ludlam at the University of Maryland, College Park, USA. This reservation includes Sandbox Reserved 1311 through Sandbox Reserved 1430. |
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DNA Structure
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
