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Sandbox Reserved 1392

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{{Sandbox_Reserved_HLSC322}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE -->
{{Sandbox_Reserved_HLSC322}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE -->
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==DNA Structure==
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==Human E-cadherin Protein==
<StructureSection load='2o72' size='340' side='right' caption='Caption for this structure' scene=''>
<StructureSection load='2o72' size='340' side='right' caption='Caption for this structure' scene=''>
This is a default text for your page ''''''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
This is a default text for your page ''''''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
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== Function ==
== Function ==
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== Disease ==
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Epithelial-cadherin (1-213), or E-cadherin is a calcium-dependent cell adhesion protein. E-cadherin regulates cell-to-cell interactions, adhesion of bacteria to mammalian cells, and
== Relevance ==
== Relevance ==
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E-cadherin is a tumor suppressor gene. Degradation or loss of function of the gene is associated with increased proliferation and metastasis of tumors. Mutations in the E-cadherin protein are linked to a series of cancers, including gastric, thyroid, colorectal, breast, and ovarian cancers.
== Structural highlights ==
== Structural highlights ==
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<scene name='77/777712/Backbone_of_molecule/1'>Back bone of E-cadherin</scene>
 
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DNA is made up of <scene name='77/777712/Base_pairs_of_dna/1'>[[base pairs]</scene>].
 
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
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E-cadherin 1 is 213 amino acids long. E-cadherin is composed of five cadherin extensions, a transmembrane region, and a cytoplasmic tail.
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<scene name='77/777712/Backbone_of_molecule/1'>Back bone of E-cadherin</scene>
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</StructureSection>
 
== References ==
== References ==
<references/>
<references/>

Revision as of 21:50, 22 February 2018

This Sandbox is Reserved from January through July 31, 2018 for use in the course HLSC322: Principles of Genetics and Genomics taught by Genevieve Houston-Ludlam at the University of Maryland, College Park, USA. This reservation includes Sandbox Reserved 1311 through Sandbox Reserved 1430.
To get started:
  • Click the edit this page tab at the top. Save the page after each step, then edit it again.
  • Click the 3D button (when editing, above the wikitext box) to insert Jmol.
  • show the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
  • Add a description of your scene. Use the buttons above the wikitext box for bold, italics, links, headlines, etc.

More help: Help:Editing

Human E-cadherin Protein

Caption for this structure

Drag the structure with the mouse to rotate
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