5n7y
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Solution structure of B. subtilis Sigma G inhibitor CsfB== | |
| - | + | <StructureSection load='5n7y' size='340' side='right' caption='[[5n7y]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5n7y]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N7Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5N7Y FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5n7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n7y OCA], [http://pdbe.org/5n7y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5n7y RCSB], [http://www.ebi.ac.uk/pdbsum/5n7y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5n7y ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GIN_BACSU GIN_BACSU]] An anti-sigma-G factor, prevents premature activation of sigma-G factor in the forespore; overexpression leads to 1000-fold reduction in spore formation, spore formation stops after engulfment (PubMed:17921305, PubMed:19497328). Overexpression also inhibits sigma-G transcription activation activity (PubMed:18208527). When both Gin and sigma-G are expressed in E.coli Gin inhibits sigma-G, strongly suggesting Gin inhibits by direct physical interaction (PubMed:19497328).<ref>PMID:17921305</ref> <ref>PMID:18208527</ref> <ref>PMID:19497328</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Alfano, C]] | ||
| + | [[Category: Atkinson, A]] | ||
| + | [[Category: Isaacson, R L]] | ||
| + | [[Category: Martinez-Lumbreras, S]] | ||
| + | [[Category: Csfb]] | ||
| + | [[Category: Dimer]] | ||
| + | [[Category: Sigma g inhibitor]] | ||
| + | [[Category: Transcription]] | ||
| + | [[Category: Zinc-finger]] | ||
Revision as of 06:17, 28 February 2018
Solution structure of B. subtilis Sigma G inhibitor CsfB
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