5o5e
From Proteopedia
(Difference between revisions)
m (Protected "5o5e" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) (V264G mutant) in complex with tunicamycin== | |
| - | + | <StructureSection load='5o5e' size='340' side='right' caption='[[5o5e]], [[Resolution|resolution]] 3.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5o5e]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O5E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5O5E FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9LH:Tunicamycin'>9LH</scene>, <scene name='pdbligand=P6L:(2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL+(8E)-OCTADEC-8-ENOATE'>P6L</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine--dolichyl-phosphate_N-acetylglucosaminephosphotransferase UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.8.15 2.7.8.15] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5o5e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o5e OCA], [http://pdbe.org/5o5e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5o5e RCSB], [http://www.ebi.ac.uk/pdbsum/5o5e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5o5e ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/GPT_HUMAN GPT_HUMAN]] DPAGT1-CDG;Congenital myasthenic syndromes with glycosylation defect. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GPT_HUMAN GPT_HUMAN]] Catalyzes the initial step in the synthesis of dolichol-P-P-oligosaccharides. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase]] | ||
| + | [[Category: Arrowsmith, C H]] | ||
| + | [[Category: Beeson, D]] | ||
| + | [[Category: Belaya, K]] | ||
| + | [[Category: Berridge, G]] | ||
| + | [[Category: Bountra, C]] | ||
| + | [[Category: Burgess-Brown, N]] | ||
| + | [[Category: Carpenter, E P]] | ||
| + | [[Category: Chalk, R]] | ||
| + | [[Category: Chu, A]] | ||
| + | [[Category: Dong, L]] | ||
| + | [[Category: Dong, Y Y]] | ||
| + | [[Category: Edwards, A M]] | ||
| + | [[Category: Goubin, S]] | ||
| + | [[Category: Kupinska, K]] | ||
| + | [[Category: Mahajan, P]] | ||
| + | [[Category: Mukhopadhyay, S]] | ||
| + | [[Category: Pike, A C.W]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Tessitore, A]] | ||
| + | [[Category: Wang, D]] | ||
| + | [[Category: Antibiotic]] | ||
| + | [[Category: Congenital myasthenic syndrome]] | ||
| + | [[Category: Integral membrane protein]] | ||
| + | [[Category: Pnpt]] | ||
| + | [[Category: Protein glycosylation]] | ||
| + | [[Category: Sgc]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 06:19, 28 February 2018
Crystal structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) (V264G mutant) in complex with tunicamycin
| |||||||||||
Categories: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase | Arrowsmith, C H | Beeson, D | Belaya, K | Berridge, G | Bountra, C | Burgess-Brown, N | Carpenter, E P | Chalk, R | Chu, A | Dong, L | Dong, Y Y | Edwards, A M | Goubin, S | Kupinska, K | Mahajan, P | Mukhopadhyay, S | Pike, A C.W | Structural genomic | Tessitore, A | Wang, D | Antibiotic | Congenital myasthenic syndrome | Integral membrane protein | Pnpt | Protein glycosylation | Sgc | Transferase
