6by7
From Proteopedia
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| - | ''' | + | {{Large structure}} |
| + | ==Folding DNA into a lipid-conjugated nano-barrel for controlled reconstitution of membrane proteins== | ||
| + | <StructureSection load='6by7' size='340' side='right' caption='[[6by7]], [[Resolution|resolution]] 7.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6by7]] is a 118 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BY7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BY7 FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6by7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6by7 OCA], [http://pdbe.org/6by7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6by7 RCSB], [http://www.ebi.ac.uk/pdbsum/6by7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6by7 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | {{Large structure}} | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Building upon DNA origami technology, we introduce a method to reconstitute a single membrane protein into a self-assembled DNA nanobarrel that scaffolds a nanodisc-like lipid environment. Compared with the membrane-scaffolding-protein nanodisc technique, our approach gives rise to defined stoichiometry, controlled sizes, as well as enhanced stability and homogeneity in membrane protein reconstitution. We further demonstrate potential applications of the DNA nanobarrels in the structural analysis of membrane proteins. | ||
| - | + | Folding DNA into a Lipid-Conjugated Nanobarrel for Controlled Reconstitution of Membrane Proteins.,Dong Y, Chen S, Zhang S, Sodroski J, Yang Z, Liu D, Mao Y Angew Chem Int Ed Engl. 2018 Feb 19;57(8):2072-2076. doi: 10.1002/anie.201710147., Epub 2018 Jan 9. PMID:29266648<ref>PMID:29266648</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | <div class="pdbe-citations 6by7" style="background-color:#fffaf0;"></div> | |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Chen, S]] | ||
| + | [[Category: Dong, Y]] | ||
| + | [[Category: Liu, D]] | ||
| + | [[Category: Mao, Y]] | ||
| + | [[Category: Sodroski, J]] | ||
[[Category: Yang, Z]] | [[Category: Yang, Z]] | ||
| - | [[Category: Sodroski, J]] | ||
| - | [[Category: Liu, D]] | ||
[[Category: Zhang, S]] | [[Category: Zhang, S]] | ||
| - | [[Category: | + | [[Category: Dna]] |
| - | [[Category: | + | [[Category: Dna nano-barrel dna origami dna assembly]] |
| - | + | ||
Revision as of 06:41, 28 February 2018
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Folding DNA into a lipid-conjugated nano-barrel for controlled reconstitution of membrane proteins
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