Adhesin

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== Disease ==
== Disease ==
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Bacterial pathogens use adhesins as a major factor in adhesion-based virulence. Adhesins serve as vaccine targets since they are essential to infection.
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Bacterial pathogens use adhesins as a major factor in adhesion-based virulence. Adhesins serve as vaccine targets since they are essential to infection<ref>PMID:10341176</ref>.
*<scene name='70/705684/Cv/2'>Adhesin PsaA complex with galactose, acetate and tert-butyl formate</scene> (PDB ID [[4f8p]]).<ref>PMID:23277582</ref>
*<scene name='70/705684/Cv/2'>Adhesin PsaA complex with galactose, acetate and tert-butyl formate</scene> (PDB ID [[4f8p]]).<ref>PMID:23277582</ref>

Revision as of 07:58, 7 March 2018

Adhesin PsaA complex with tert-butyl formate and galactose (stick model) (PDB ID 4f8p)

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3D Structures of adhesin

Updated on 07-March-2018


References

  1. Klemm P, Schembri MA. Bacterial adhesins: function and structure. Int J Med Microbiol. 2000 Mar;290(1):27-35. PMID:11043979 doi:http://dx.doi.org/10.1016/S1438-4221(00)80102-2
  2. Wizemann TM, Adamou JE, Langermann S. Adhesins as targets for vaccine development. Emerg Infect Dis. 1999 May-Jun;5(3):395-403. doi: 10.3201/eid0503.990310. PMID:10341176 doi:http://dx.doi.org/10.3201/eid0503.990310
  3. Bao R, Nair MK, Tang WK, Esser L, Sadhukhan A, Holland RL, Xia D, Schifferli DM. Structural basis for the specific recognition of dual receptors by the homopolymeric pH 6 antigen (Psa) fimbriae of Yersinia pestis. Proc Natl Acad Sci U S A. 2013 Jan 15;110(3):1065-70. doi:, 10.1073/pnas.1212431110. Epub 2012 Dec 31. PMID:23277582 doi:10.1073/pnas.1212431110

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